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Tears at the Heart of Things: Moral Distress Among Principals of Canadian-Accredited Schools in China
DownloadSpring 2024
Moral distress arises when a person is aware of a moral problem, acknowledges a moral responsibility to act, yet is constrained from following a course of action congruent with their own moral judgement (Nathaniel, 2006; Jameton, 1984). Being hindered from doing what one believes to be morally...
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Evaluation of Targeted Selective Inhibitors to Enhance Temozolomide Treatment Sensitivity in Acute Myeloid Leukemia
DownloadSpring 2024
Temozolomide (TMZ) is an alkylating agent with limited activity in acute myeloid leukemia (AML). The DNA repair enzyme O6-methylguanine methyltransferase (MGMT) enhances tumor cell resistance to TMZ. B-cell lymphoma-2 (BCL-2) and mouse double minute 2 homology (MDM2) are proteins involved in AML...
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Applying a community-based monitoring framework to enteric bacteria monitoring and microbial source tracking
DownloadSpring 2024
Using microbial source tracking (MST) to find possible causes of fecal contamination in freshwater systems via quantitative polymerase chain reaction (qPCR) is a robust field with ever increasing application. Rural lakes have been less studied using this technique but there is high potential for...
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Spring 2024
Integrating gravity into the Standard Model (SM) of particle physics presents a chal- lenge in formulating a unified theory of all interactions. Quantum gravity inherits a principle from quantum field theories. Here, gravity is interpreted as a field. This conceptualization leads to the...
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Spring 2024
Nitrogen is an important component for our ecosystems, which accounts for 80% of chemical elements in the atmosphere. Ammonia nitrogen is one of the most concerned constituents for the environment. The municipal wastewater contributes the greatest amount of nitrogen into surface water and...
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Towards Practical Offline Reinforcement Learning: Sample Efficient Policy Selection and Evaluation
DownloadSpring 2024
Offline reinforcement learning (RL) involves learning policies from datasets, rather than online interaction. The dissertation first investigates a critical component in offline RL: offline policy selection (OPS). Given that most offline RL algorithms require careful hyperparameter tuning, we...
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Spring 2024
Steam-assisted gravity drainage (SAGD) has proved to be a technically and commercially successful methodology for recovering heavy-oil in Canada. At present, there are 22 commercial SAGD projects with over 300 pads and 2,700 well pairs, contributing to over 1.5 million bbl/day of production. The...
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Novel Treatments for Intestinal Failure Explored in Neonatal Piglets with Short Bowel Syndrome: Focusing on the Microbiome, Sepsis and Trophic Factors
DownloadSpring 2024
Short bowel syndrome (SBS) is the leading cause of intestinal failure (IF) in infants, and occurs when there is a significant loss of intestine due to acquired or congenital reasons, leading to infants being unable to absorb sufficient nutrients for survival and growth. SBS traditionally had a...
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Spring 2024
This study characterized flare-like flame emissions and improved methods of reducing flare emissions during well completion operations in the upstream oil and gas industries. Flowback fluids are water-based solutions that return to the earth’s surface with extracted oil and gas during and after...
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Spring 2024
Nanotechnology has advanced in recent years to the extent that custom-tailored structures of high regularity can now be synthesized with high precision. Single-digit nanochannels (SDNs), referring to nanochannels with a diameter or conduit width of less than 10 nanometers, present unique...