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- 38Medicine and Dentistry, Faculty of/Alberta Research Centre for Health Evidence (ARCHE)
- 35Medicine and Dentistry, Faculty of/Journal Articles (Medicine and Dentistry)
- 9Oncology, Department of
- 9Oncology, Department of/Medical Physics
- 5University of Alberta Library
- 22Hartling, L.
- 17Klassen, T. P.
- 11Hartling, Lisa
- 11Schulz, Richard
- 9Babenko, Oksana
- 9De Zanche, Nicola
- 12Systematic reviews
- 10Pediatrics
- 5Child health
- 5Meta-analysis
- 5Randomized controlled trials
- 4Drug therapy
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Angiostatin inhibits endothelial MMP-2 and MMP-14 expression: A hypoxia specific mechanism of action
Download2013
Zielnik-Drabik, B., Jurasz, P., Radziwon-Balicka, A., Moncada de la Rosa, C., Ramer, C.
Angiostatin is an angiogenesis inhibitor in part generated by and released from platelets. Since platelets upon thrombus formation can give rise to areas of hypoxia, we investigated the effects of angiostatin on endothelial cell migration and apoptosis during hypoxia. Human microvascular...
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Applying the risk of bias tool in a systematic review of combination long-acting beta-agonists and inhaled corticosteroids for persistent asthma.
Download2011
Seida, J., Vandermeer, B., Hartling, L., Dryden, D. M., Rowe, B. H., Bond, K.
Background The Risk of Bias (RoB) tool is used to assess internal validity of randomized controlled trials (RCTs). Our objectives were to: 1) evaluate inter-rater agreement of the RoB tool; 2) determine the time to access supplemental study information; 3) compare the RoB tool with the Jadad...
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2020-11-02
Sloychuk, Janelle, Szafran, Olga, Duerksen, Kimberley, Babenko, Oksana
Introduction: In medical practice, a mastery mindset is important for engaging in lifelong learning. The objective of this study was to examine the association between family medicine residents’ scores on mindset measures and their performance on in-training examinations (ITE). Methods: This was...
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Association of Physicians’ Self-Compassion with Work Engagement, Exhaustion, and Professional Life Satisfaction
Download2019-02-12
Babenko, Oksana, Mosewich, Amber, Lee, Ann, Koppula, Sudha
Self-compassion has shown promise as an adaptive resource for coping with uncertainties and challenges. This study examined the relationship between self-compassion and professional wellbeing (work engagement, exhaustion, and professional life satisfaction) of physicians, who frequently face...
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Behavioural and developmental interventions for autism spectrum disorder: a clinical systematic review.
Download2008
Clark, B., Hartling, L., Krebs Seida, J., Karkhaneh, M., Smith, V., Tjosvold, L., Ospina, M. B.
BACKGROUND: Much controversy exists regarding the clinical efficacy of behavioural and developmental interventions for improving the core symptoms of autism spectrum disorders (ASD). We conducted a systematic review to summarize the evidence on the effectiveness of behavioural and developmental...
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2005
Klassen, T. P., Lee, D., Tubman, M., Majumdar, S. R., Friesen, C.
Recommendations for improved patients’ safety, specifically the safety of products containing potassium, are often based on practice guidelines and untested recommendations widely endorsed by various experts or organisations Valid and empirical evidence to support or discourage implementation of...
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Brief Emergency Department Interventions for Youth Who Use Alcohol and Other Drugs: A Systematic Review
Download2013
Gokiert, Rebecca, Wild, T. Cameron, Newton, Amanda S., Mabood, Neelam, Ata, Nicole, Dong, Kathryn, Ali, Samina, Hartling, Lisa, Vandermeer, Ben, Tjosvold, Lisa
Objective: Brief intervention (BI) is recommended for use with youth who use alcohol and other drugs. Emergency departments (EDs) can provide BIs at a time directly linked to harmful and hazardous use. The objective of this systematic review was to determine the effectiveness of EDbased BIs....
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Cardiomyocyte overexpression of iNOS in mice results in peroxynitrite generation, heart block, and sudden death
Download2002-01-01
Mungrue, Imran N., Gros, Robert, You, Xiaomang, Pirani, Asif, Azad, Azar, Csont, Tamas, Husain, Mansoor, Schulz, Richard
Increased inducible nitric oxide synthase (iNOS) expression is a component of the immune response and has been demonstrated in cardiomyocytes in septic shock, myocarditis, transplant rejection, ischemia, and dilated cardiomyopathy. To explore whether the consequences of such expression are...
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2017-01-06
Bording-Jorgensen, M. , O'keefe, S. , Mason, A., Warren, K., Patterson J., Jovel, J., Wong, G., Wang, W.
Multiple sclerosis (MS) is a common cause of non-traumatic neurologic disability with high incidence in many developed countries. Although the etiology of the disease remains elusive, it is thought to entail genetic and environmental causes, and microbial pathogens have also been envisioned as...
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Children are not just small adults: the urgent need for high-quality trial evidence in children.
Download2008
Offringa, M., Hartling, L., Craig, J. C., Klassen, T. P.
Children are often touted as being very important members of society because they represent our future. Optimizing their health outcomes has the potential for a huge impact on public health because children are at an early stage in the life trajectory. But it is often unclear how society...