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Spring 2011
Human Cytomegalovirus (HCMV) is the most common cause of congenital infection in newborns. One mechanism for this virus to reach the fetus is to cross the placenta through the syncytiotrophoblast layer. Accumulation and protection of pathogens in the syncytiotrophoblast could affect the systemic...
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The Role of Matrix Metalloproteinase-2 in the Pathophysiology of a Reduced Utero-Placental Perfusion Pressure Model of Preeclampsia
DownloadFall 2012
Preeclampsia is a leading cause of maternal and fetal morbidity/mortality and induced preterm birth. Endothelin-1 (ET-1) is a potent vasoactive agent, shown to be involved in the vascular endothelial dysfunction of preeclampsia. Big endothelin (bigET) is cleaved to ET-1 by several enzymes...
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