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Skip to Search Results- 2Hegadoren, Kathleen M.
- 1Adu, Medard Kofi
- 1Al-Ghamdi,Mohammad S
- 1Al-Nuaimi, Saleem K
- 1Amritraj, Asha
- 1Amusan, Precious
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Spring 2017
Neurocysticercosis, the major global cause of acquired epilepsy, is a parasitic disease caused by Taenia solium larvae. Patients may have seizures whether larvae in brain are alive or degenerated (calcified). We assessed whether parasitic lesions produce changes in structural brain scans that are...
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Spring 2021
Alcohol use disorder (AUD) is one of the most prevalent, harmful, and costly preventable disorders in the world. AUD is associated with wide-spread structural and functional brain deficits, which are at least partially reversible with sustained abstinence. The most rapid recovery is thought to...
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Non-verbal cognitive domain functions positively associate with mildly elevated fasting blood glucose in individuals presenting with a psychotic illness
DownloadFall 2017
Background: The metabolic syndrome (MetS) is a cluster of biological parameters that have been identified as significant risk factors in the development of cardiovascular disease. The relevance of MetS to the psychiatric population has been demonstrated in that having severe mental illness (SMI)...
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Novel properties of the multifaceted drug phenelzine and its metabolite β-phenylethylidenehydrazine
DownloadFall 2015
Phenelzine is a monoamine oxidase (MAO) inhibitor that has been used for the treatment of depression and anxiety disorders since the 1960s. In recent years, there has been renewed interest in this drug following reports of its neuroprotective properties in animal models of cerebral ischemia,...
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Pharmacogenomics for Psychiatry: Focusing on Drug Metabolizing Enzymes and Transporters, with Validated Methodology for CYP2D6 and CYP2C19 Including for a Novel Sub-Haplotype
DownloadSpring 2022
Pharmacogenomics (PGx) is interested in the impact individual genetic makeup has on a patient’s response to pharmacological agents. In clinical practice, PGx has the potential of reducing adverse drug reactions (ADRs), which cost Canada $65 million dollars in the year 2018, as well as enhancing...
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Phasic Electrodermal Activity in Schizophrenia: Skin Conductance Response in Unmedicated Schizophrenic Patients in Comparison to Normal Controls
DownloadSpring 2012
Stimulus-elicited (phasic) skin conductance responses (SCRs) to indifferent stimuli have often been employed to examine abnormalities in orienting (allocation of attention) in studies of schizophrenia. Most previous studies have examined phasic activity only during habituation paradigms....
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Plasma Levels of Neuroactive Steroids in Panic Disorder Patients and Healthy Volunteers Following Pentagastrin versus Placebo Injections
DownloadFall 2016
Panic disorder is an anxiety illness that can be quite debilitating and costly to society. To date there is no real cure for panic disorder and current methods of treatment are suboptimal. Given the level of morbidity and societal cost of panic disorder, further research and development of...