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Fall 2011
Calnexin is a ubiquitously expressed endoplasmic reticulum chaperone that in conjunction with the similar endoplasmic reticulum chaperone calreticulin and protein disulfide isomerase ERp57, is responsible for protein folding and quality control in the secretory pathway. We generated a...
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Development and Application of Quantitative Gradient-Echo MRI Techniques for Assessment of Iron and Myelin in the Multiple Sclerosis Brain
DownloadFall 2018
Multiple Sclerosis (MS) is a progressive autoimmune and neurodegenerative disease of the Central Nervous System that results in demyelination and neuronal/axonal loss. Along with clinical evaluation, Magnetic Resonance Imaging (MRI) is the gold standard modality for diagnosing and monitoring MS,...
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Fall 2021
Tracking myelination and demyelination in the brain is a crucial part of studies on neurodegenerative diseases such as Multiple Sclerosis (MS). Classic MRI techniques are unable to provide enough information about the pathology of tracts and lesions. Multi-component analysis of multi-echo data...