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- 4Mixed methods
- 3Systematic reviews
- 2Pediatrics
- 1Adults
- 1Antenatal care
- 8Nursing, Faculty of
- 6Medicine and Dentistry, Faculty of
- 6Medicine and Dentistry, Faculty of/Alberta Research Centre for Health Evidence (ARCHE)
- 5Nursing, Faculty of/Health Systems
- 3Nursing, Faculty of/Health Equity
- 2Nursing, Faculty of/Chronicity
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A randomized, controlled trial of ginseng consumption on the immune response to a moderate exercise stress protocol in non-athletic women
Download2010
McCargar, Linda J., Harber, Vicki J., Field, Catherine J., Biondo, Patricia D.
Background: Ginseng is a popular herbal remedy that has been proposed to increase resistance to stress and enhance immune function. Regular moderate exercise results in an acute physiological stress that affects immune function. Objective: This study was conducted to investigate the effects of...
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2011
Worthington, C., Wong, T., Jackson, R., Archibald, C., Sommerfeldt, S., Prentice, T., Mill, J.E., Myers, T.
The purpose of the current study was to explore the HIV testing behaviours of Canadian Aboriginal youth, who have an increased vulnerability to HIV infection. In our mixed method study, 28 Aboriginal youth participated in an in-depth, semi-structured interview and 413 youth from all ten provinces...
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Applying the risk of bias tool in a systematic review of combination long-acting beta-agonists and inhaled corticosteroids for persistent asthma.
Download2011
Seida, J., Vandermeer, B., Hartling, L., Dryden, D. M., Rowe, B. H., Bond, K.
Background The Risk of Bias (RoB) tool is used to assess internal validity of randomized controlled trials (RCTs). Our objectives were to: 1) evaluate inter-rater agreement of the RoB tool; 2) determine the time to access supplemental study information; 3) compare the RoB tool with the Jadad...
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Behavioural and developmental interventions for autism spectrum disorder: a clinical systematic review.
Download2008
Clark, B., Hartling, L., Krebs Seida, J., Karkhaneh, M., Smith, V., Tjosvold, L., Ospina, M. B.
BACKGROUND: Much controversy exists regarding the clinical efficacy of behavioural and developmental interventions for improving the core symptoms of autism spectrum disorders (ASD). We conducted a systematic review to summarize the evidence on the effectiveness of behavioural and developmental...
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Comparing the feasibility, acceptability, clinical-, and cost-effectiveness of mental health e-screening to paper-based screening on the detection of depression, anxiety, and psychosocial risk in pregnant women: A study protocol of a randomized, parallel-group, superiority trial.
Download2014
Sword, W., Ohinmaa, A., Lasiuk, G., Giallo, R., Kingston, D., van Zanten, S., Biringer, A., Austin, M., Hegadoren, K., Lane-Smith, M., McDonald, S., MacQueen, G.
Background Stress, depression, and anxiety affect 15% to 25% of pregnant women. However, substantial barriers to psychosocial assessment exist, resulting in less than 20% of prenatal care providers assessing and treating mental health problems. Moreover, pregnant women are often reluctant to...
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Do health care institutions value research? A mixed methods study of barriers and facilitators to methodological rigor in pediatric randomized trials.
Download2012
Scott, S. D., Hamm, M. P., Hartling, L., Klassen, T. P., Moher, D.
Background Pediatric randomized controlled trials (RCTs) are susceptible to a high risk of bias. We examined the barriers and facilitators that pediatric trialists face in the design and conduct of unbiased trials. Methods We used a mixed methods design, with semi-structured interviews building...
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2013
Scott, S. D., Moher, D., Klassen, T. P., Hartling, L., Hamm, M. P.
Introduction A research-practice gap exists between what is known about conducting methodologically rigorous randomized controlled trials (RCTs) and what is done. Evidence consistently shows that pediatric RCTs are susceptible to high risk of bias; therefore novel methods of influencing the...
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Effectiveness of knowledge translation interventions to improve cancer pain management (Protocol)
Download2008
Biondo, P., Armijo Olivo, S., Haggen, N.A., Fainsinger, R., Stiles, C., Cummings, G.G.
This is the protocol for a review and there is no abstract. The objectives are as follows: The objective of this review is to determine the effectiveness of interventions targeting behaviour and facilitating uptake of new knowledge by healthcare practitioners, patients and their family caregivers...
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Primary Outcomes Reporting in Trials (PORTal): a systematic review of inadequate reporting in pediatric randomized controlled trials
Download2016-09-22
Adams, Denise, Terwee, Caroline B., Hansraj, Namrata, Hartling, Lisa, Vohra, Sunita, Bhaloo, Zafira, Liu, Yali
Objective: Conduct a systematic review of pediatric randomized controlled trials published in high impact journals to assess the reporting of primary outcomes and the psychometric properties of their measures. Study Design and Setting: Systematic review with screening and simultaneous data...
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Quantifying bias in randomized controlled trials in child health: a meta-epidemiological study.
Download2014
Hartling, L., Vandermeer, B., Dryden, D. M., Fernandes, R. M., Hamm, M. P.
Objective: To quantify bias related to specific methodological characteristics in child-relevant randomized controlled trials (RCTs). Design: Meta-epidemiological study. Data Sources: We identified systematic reviews containing a meta-analysis with 10–40 RCTs that were relevant to child health in...