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Spring 2013

Montgomery, Benjamin Christian Sivert

A balance of intracellular signaling events control immune cell functions. In innate immunity, many of these signals are transmitted by subsets of cell surface proteins known as immunoregulatory receptors. Through their recognition of a diverse array of molecules these receptors effectively...

Fall 2020

Fei,Chenjie

Across vertebrates, innate immune cells are capable of initiating a range of potent effector responses that are designed to destroy or contain foreign microbial invaders. The execution and regulation of various innate cellular responses is mediated by a dedicated repertoire of cell...

Fall 2013

Cortes, Herman D

In response to pathogens, immune cells induce protective effector functions, such as degranulation, phagocytosis and cytokine secretion, which are initiated by stimulatory or inhibitory immunoregulatory receptors expressed on leukocytes. Using a fish immunological model system, the focus of my...

Fall 2024

Wang, Jiahui

Originally discovered in the channel catfish, Ictalurus punctatus leukocyte immune-type receptors (IpLITRs) are members of the immunoglobulin superfamily (IgSF) and several of their transcripts are known to be expressed in a variety of catfish innate and adaptive immune cells. Phylogenetically,...

Spring 2020

Gurupalli, Hima V

In response to foreign invaders, innate immune cells use cell surface-expressed receptors to trigger intracellular signalling cascades that control various effector responses designed to destroy microbes. These specialized receptors are known as immunoregulatory receptors and structurally they...

Spring 2023

Niemand, Rikus R

To combat microbial invaders, immune cells elicit a range of potent antimicrobial effector responses coordinated by complex intracellular signalling events. These events are initiated by the engagement of cell surface-expressed proteins, termed immunoregulatory receptors, that bind to and...