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1995
Abstract: A cluster of genes of the CYP6 family was found in a series of overlapping lambda DASH clones from a genomic library of the house fly, Musca domestica, Four complete genes, CYP6A3, CYP6A4, CYP6A5, and CYP6C1, and fragments of two other genes, CYP6A6 and CYP6C2, were closely linked on a...
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Amino acid polymorphisms in strictly conserved domains of a P-type ATPase HMA5 are involved in the mechanism of copper tolerance variation in Arabidopsis
Download2008
Kimura, K., Southron-Francis, J. L., Iuchi, S., Furuzawa, A., Taylor, G. J., Kobayashi, Y., Koyama, H., Kobayashi, M., Kuroda, K.
Copper (Cu) is an essential element in plant nutrition, but it inhibits the growth of roots at low concentrations. Accessions of Arabidopsis ( Arabidopsis thaliana) vary in their tolerance to Cu. To understand the molecular mechanism of Cu tolerance in Arabidopsis, we performed quantitative trait...
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An alternative physiological role for the EmhABC efflux pump in Pseudomonas fluorescens cLP6a
Download2011
Background Efflux pumps belonging to the resistance-nodulation-division (RND) superfamily in bacteria are involved in antibiotic resistance and solvent tolerance but have an unknown physiological role. EmhABC, a RND-type efflux pump in Pseudomonas fluorescens strain cLP6a, extrudes hydrophobic...
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CS23D: A web server for rapid protein structure generation using NMR chemical shifts and sequence data
Download2008
Wishart, D.S., Berjanskii, M., Arndt, D., Lin, G., Tang, P., Zhou, J.
CS23D (chemical shift to 3D structure) is a web server for rapidly generating accurate 3D protein structures using only assigned nuclear magnetic resonance (NMR) chemical shifts and sequence data as input. Unlike conventional NMR methods, CS23D requires no NOE and/or J-coupling data to perform...
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Development of an assay for the identification of campylobacter bacteriophage receptor binding proteins
Development of an assay for the identification of campylobacter bacteriophage receptor binding proteins
Download2012-10-25
Bacterial viruses (phages) are ubiquitous in the environment and are believed to target every bacterial species. Phages utilize receptor binding proteins (RBPs) to bind specifically to their host cell surface. The Campylobacter jejuni phage NCTC 12673 RBP and its capsular polysaccharide (CPS)...
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Genomic sequence and activity of KS10, a transposable phage of the Burkholderia cepacia complex
Download2008
Seed, K.D., Lynch, K.H., Dennis, J.J., Goudie, A.D., Wishart, D.S., Shrivastava, S., Stothard, P.
Background: The Burkholderia cepacia complex (BCC) is a versatile group of Gram negative organisms that can be found throughout the environment in sources such as soil, water, and plants. While BCC bacteria can be involved in beneficial interactions with plants, they are also considered...
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GERp95, a membrane-associated protein that belongs to a family of proteins involved in stem cell differentiation
Download1999
DiMattia, G.E., Hansen, D., Tahbaz, N., Hobman, T.C., Hendricks, L.C., Pilgrim, D., Cikaluk, D.E.
A panel of mAbs was elicited against intracellular membrane fractions from rat pancreas. One of the antibodies reacted with a 95-kDa protein that localizes primarily to the Golgi complex or the endoplasmic reticulum (ER), depending on cell type. The corresponding cDNA was cloned and sequenced and...
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2007
Seligmann, B., Deyholos, M., Kris, R. M., Felder, S., Botros, I., Galbraith, D. W., Martel, R., Hinton, J., Lambert, G. M.
High-throughput gene expression analysis of genes expressed during salt stress was performed using a novel multiplexed quantitative nuclease protection assay that involves customized DNA microarrays printed within the individual wells of 96-well plates. The levels of expression of the transcripts...
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2009
Lewis, A., Wishart, D.S., Guo, A.C., Gautam, B., Tzur, D., Sobsey, C.A., Shaykhutdinov, R., Fradette, R., De Souza, A., Cruz, J.A., Xiong, Y., Bouatra, S., Mandal, R., Psychogios, N., Sinelnikov, I., Vogel, H.J., Fang, L., Peng, J., Xia, J., Li, L., Knox, C., Shrivastava, S., Clements, M., Lim, E., Eisner, R., Cheng, D., Dawe, M., Zuniga, A., Young, N., Jia, L., Grenier, R., Hau, D.D., Huang, P., Nazyrova, A., Liu, P., Forsythe, I., Dong, E., Clive, D.
The Human Metabolome Database (HMDB, http:// www.hmdb.ca (http://www.hmdb.ca)) is a richly annotated resource that is designed to address the broad needs of biochemists, clinical chemists, physicians, medical geneticists, nutritionists and members of the metabolomics community. Since its first...
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Hymenolepis diminuta (Cestoda) induces changes in expression of select genes of Tribolium confusum (Coleoptera)
Download2009
Belosevic, M., Shostak, A. W., Hitchen, S. J.
The flour beetle Tribolium confusum is a common experimental intermediate host for the tapeworm Hymenolepis diminuta, but while many aspects of their host-parasite interactions have been determined to have genetic basis, the genes involved have not been identified. In this paper, we report on the...