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Skip to Search Results- 3Hepatocellular carcinoma
- 1Apoptosis
- 1Cholangiocarcinoma
- 1Cholangiocellular carcinoma
- 1End-stage liver diseases
- 1Influenza
- 1Bamforth, Fiona (Co-supervisor, Department of Laboratory Medicine & Pathology)
- 1Keelan, Monika (Department of Laboratory Medicine and Pathology)
- 1Mason, Andrew (Department of Medicine)
- 1Sergi, Consolato (Department of Laboratory Medicine and Pathology and Department of Pediatrics)
- 1Sergi, Consolato (Supervisor, Department of Laboratory Medicine & Pathology)
- 1Wong, Gane (Department of Medicine)
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Application of Next Generation Sequencing and Bioinformatic Approaches to the Study of Influenza Virus Strains and MiRNA Profiling in Liver Diseases
DownloadSpring 2016
Analysis and interpretation of next generation sequencing data has posed a significant challenge to researchers, especially to those who are not equipped with expertise in bioinformatics. In this thesis, I investigated three different biomedical questions using NGS and bioinformatic approaches,...
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Differential Expression of TWSG1, BMP4 and Shh Morphogens Signaling Proteins in Hepatocellular Carcinoma and Cholangiocellular Carcinoma
DownloadSpring 2014
Hepatocellular carcinoma (HCC) and cholangiocellular carcinoma (CCA) constitute two of the most common liver malignancies in adults. The molecular mechanisms underlying their development remain poorly understood. Morphogen proteins, including the hedgehog and the bone morphogenetic proteins...
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Mitochondrial Dysfunction and Induction of Apoptosis in Hepatocellular Carcinoma and Cholangiocarcinoma Cell Lines by Thymoquinone
DownloadSpring 2015
Thymoquinone, the plant-based bioactive constituent derived from the volatile oil of Nigella sativa, has been shown to possess considerable anti-neoplastic activity. The present study aimed to investigate the anti-tumour property of TQ against hepatocellular carcinoma (HepG2) and...