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- 1Desorption Electrospray Ionization
- 1Electrospray Ionization
- 1Liquid Sample Desorption Electrospray Ionization
- 1Liquid sample DESI-MS
- 1Mass-spectrometry
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Fall 2013
This thesis describes the studying of electrospray ionization (ESI) process and the application of the direct ESI-MS assay to study noncovalent carbohydrate-protein interactions in vitro. Protein unfolding induced by ESI process was first investigated. It is proposed that the Coulombic repulsion...
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Fall 2016
This thesis describes the development of mass spectrometry methods to study protein-ligand interactions in vitro. Liquid sample desorption electrospray ionization mass spectrometry (liquid sample DESI-MS) was first applied to quantify protein-carbohydrate interactions in aqueous ammonium acetate...
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Study of Non-Covalent Multisubunit Protein-Carbohydrate Interactions by Electrospray Ionization Mass Spectrometry
DownloadFall 2013
This thesis describes the development and application of electrospray ionization mass spectrometry (ESI-MS) based techniques to investigate protein-carbohydrate interactions in vitro. A catch-and-release electrospray ionization mass spectrometry (CaR-ESI-MS) assay was developed for the...