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Diagnosing Clinically Significant Dehydration in Children with Acute Gastroenteritis Using Noninvasive Methods: A Meta-Analysis
Download2015
Milne, Andrea, Hartling, Lisa, Vandermeer, Ben, Freedman, Stephen B.
OBJECTIVE: To determine the most accurate, noninvasive method of assessing dehydration. STUDY DESIGN: The following data sources were searched: electronic databases, gray literature, scientific meetings, reference lists, and authors of unpublished studies. Eligible studies were comparative...
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Do health care institutions value research? A mixed methods study of barriers and facilitators to methodological rigor in pediatric randomized trials.
Download2012
Scott, S. D., Hamm, M. P., Hartling, L., Klassen, T. P., Moher, D.
Background Pediatric randomized controlled trials (RCTs) are susceptible to a high risk of bias. We examined the barriers and facilitators that pediatric trialists face in the design and conduct of unbiased trials. Methods We used a mixed methods design, with semi-structured interviews building...
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2013
Scott, S. D., Moher, D., Klassen, T. P., Hartling, L., Hamm, M. P.
Introduction A research-practice gap exists between what is known about conducting methodologically rigorous randomized controlled trials (RCTs) and what is done. Evidence consistently shows that pediatric RCTs are susceptible to high risk of bias; therefore novel methods of influencing the...
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Fall 2014
Infant face and throat replicas are used in research laboratories to compare the effectiveness of different valved holding chamber and face mask designs. The use of soft face models is thought to provide a better representation of mask dead volume and face mask seal than hard face models....
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2008
Leon, H., Tsuyuki, R.T., Dorgan, M., Chatterley, T., Sivakumaran, S., Shibata, M.C.
Abstract: Objective To synthesise the literature on the effects of fish oil - docosahexaenoic acid ( DHA) and eicosapentaenoic acid ( EPA) - on mortality and arrhythmias and to explore dose response and formulation effects. Design Systematic review and meta- analysis. Data sources Medline,...
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Effectiveness of knowledge translation interventions to improve cancer pain management (Protocol)
Download2008
Biondo, P., Armijo Olivo, S., Haggen, N.A., Fainsinger, R., Stiles, C., Cummings, G.G.
This is the protocol for a review and there is no abstract. The objectives are as follows: The objective of this review is to determine the effectiveness of interventions targeting behaviour and facilitating uptake of new knowledge by healthcare practitioners, patients and their family caregivers...
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Fall 2020
Introduction By 2030, 1/100 Canadians are predicted to be diagnosed with inflammatory bowel diseases (IBD); approximately 25% of cases are diagnosed in children. IBD include Crohn disease (CD) and ulcerative colitis (UC), and manifest with chronic gastrointestinal inflammation. Pathogenesis...
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Efficacy and safety of exogenous melatonin for secondary sleep disorders and sleep disorders accompanying sleep restriction: meta-analysis.
Download2006
Vandermeer, B., Hartling, L., Buscemi, N.., Baker, G., Klassen, T. P., Vohra, S., Pandya, R., Tjosvold, L., Hooton, N.
Objective To conduct a systematic review of the efficacy and safety of exogenous melatonin in managing secondary sleep disorders and sleep disorders accompanying sleep restriction, such as jet lag and shiftwork disorder. Data sources 13 electronic databases and reference lists of relevant...
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Enrollment in Multidisciplinary Clinical Care for Pediatric Weight Management: Predictors, Reasons, Facilitators, and Recommendations
DownloadFall 2017
Background: One-third of Canadian children meet the criteria for overweight or obesity. While multidisciplinary clinical care (MCC) can be effective to manage pediatric obesity, many eligible children are not referred to this level of care and many of those who are referred do not enroll in...
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2013-02-15
Klassen, Terry P., Plint, Amy C., Vandermeer, Ben, Tjosvold, Lisa, Hartling, Lisa, Fernandes, Ricardo M., Patel, Hema, Bialy, Liza M., Johnson, David W.
Background: Bronchodilators are commonly used for acute bronchiolitis, despite uncertain effectiveness. Objectives: To examine the efficacy and safety of epinephrine in children less than two with acute viral bronchiolitis. Search methods: We searched CENTRAL (2010, Issue 3) which contains the...