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- 3Bell, Rhonda C.
- 3Bruce, Sharon G.
- 3Riediger, Natalie D.
- 2Al Sayah, Fatima
- 2Bell, R.
- 41Graduate and Postdoctoral Studies (GPS), Faculty of
- 41Graduate and Postdoctoral Studies (GPS), Faculty of/Theses and Dissertations
- 10School of Public Health
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- 7Agricultural, Food and Nutritional Science, Department of/Journal Articles (Agricultural, Food and Nutritional Science)
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Diabetes-prone BioBreeding rats do not have a normal immune response when weaned to a diet containing fermentable fibre
Download2004
Bell, Rhonda C., Field, Catherine J., Stillie, RoseMarie
Diet is known to modulate the development of diabetes in diabetes-prone BioBreeding (BBdp) rats. The objective of the present study was to determine the effect of fermentable fibre (FF) on immune function in BBdp and diabetes-resistant BioBreeding (BBdr) rats after weaning. Weanling BBdp...
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Drug Exposure Definition and Healthy User Bias Impacts on the Evaluation of Oral Anti Hyperglycemic Therapies
DownloadFall 2017
Accurate estimation of medication use is an essential component of any pharmacoepidemiological research as exposure misclassification will threaten study validity and lead to spurious associations. Many pharmacoepidemiological studies use simple definitions, such as the categorical “any versus no...
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Fall 2011
Islet transplantation is promising treatment for certain patients with type 1 diabetes who experience recurrent episodes of hypoglycemia with unawareness. One opportunity to improve on islet transplant outcomes and potentially broaden the recipient population, is to reduce the early post...
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Exploring the Relationship Between Depression and Adherence in Individuals with Type 2 Diabetes
DownloadFall 2020
Background: Depression is a well-known risk factor for poor medication adherence in individuals with diabetes; however, this association is based on cross-sectional and cohort studies measuring adherence after depression is diagnosed. Symptoms of depression often progress before medical...
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Feeding high oleic acid Canola oil or olive oil alters inflammation, insulin resistance and lipid metabolism in a rodent model of diet induced obesity
DownloadFall 2011
To determine the efficacy of feeding monounsaturated fatty acids (MUFA) via a high MUFA Canola oil on T2D risk factors diet induced obese rats were fed either a low fat diet (LF), a high fat low MUFA diet (HF), a high fat high MUFA olive oil diet (OO), or a high fat high MUFA Canola oil diet...
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Fall 2013
There is a general agreement that a relationship exists between health literacy (HL) and health outcomes. Nonetheless, there are critical gaps in the measurement of HL and in the evidence on the impact of inadequate HL on health outcomes, especially in the diabetes population. These gaps need to...
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Fall 2013
There is a general agreement that a relationship exists between health literacy (HL) and health outcomes. Nonetheless, there are critical gaps in the measurement of HL and in the evidence on the impact of inadequate HL on health outcomes, especially in the diabetes population. These gaps need to...
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High-fructose feeding of streptozotocin-diabetic rats is associated with increased cataract formation and increased oxidative stress in the kidney
Download2000
Sivak, J. , Storr, K. C., Carlson, J. C., Bell, R. C., Herbert, K.
We examined the effects of high-fructose (FR) feeding on the development of diabetic complications in the lens and the kidney of streptozotocin (STZ)-diabetic rats. Male Wistar Furth rats were treated with one of two doses of STZ (HIGH STZ, 55 mg/kg body weight; MOD STZ, 35 mg/kg body weight) or...
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Histories, Bodies, Stories, Hungers: The Colonial Origins of Diabetes as a Health Disparity among Indigenous Peoples in Canada
DownloadFall 2018
Indigenous people in Canada suffer disproportionately from health disparities, such as obesity and type 2 diabetes, and I have explored these health disparities among Indigenous peoples through the lens of embodiment. Framed within the Developmental Origins of Health and Disease (DOHaD) model,...
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Impaired de novo choline synthesis explains why phosphatidylethanolamine N-methyltransferase-deficient mice are protected from diet-induced obesity
Download2010
Kuo, Ming-Shang, Dyck, Jason R. B., Sletten, Torunn, Proctor, Spencer D., Jacobs, René L., Lingrell, Susanne, Cao, Guoqing, Peake, David A., Kennedy, Brian P., Zhao, Yang, Vance, Dennis E., Koonen, Debby P. Y., Su, Brian
Phosphatidylcholine (PC) is synthesized from choline via the CDP-choline pathway. Liver cells can also synthesize PC via the sequential methylation of phosphatidylethanolamine, catalyzed by phosphatidylethanolamine N-methyltransferase (PEMT). The current study investigates whether or not hepatic...