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Skip to Search Results- 1Aguirre Monroy, Angelica M
- 1Alam, Kazi, MM
- 1Baillie, Devin MJ
- 1Baleja, James D.
- 1Booker, Brandon K.
- 1Chehel Amirani, Morteza
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Miniaturization of Microwave to Millimeter-Wave Integrated Waveguides and their Applications
DownloadFall 2019
The integration of waveguide technology at the planar level has been a crucial development for the successful realization of 5G, the future fifth generation cellular network. The demand for mobile networks with faster speeds, lower latencies, and denser connectivity scenarios continues to drive...
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Molecular Dynamics Simulations of Polyethylenimine Mediated Nucleic Acid Complexation with Implications for Non-viral Gene Delivery
DownloadSpring 2013
Gene therapy is a promising therapeutic technique that involves delivering nucleic acids into cells. Polycations have evolved into a major category of gene carriers. Polyethylenimine (PEI) is one of the most effective polycationic carriers. Furthermore, modifying PEI with certain lipophilic...
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Spring 2016
Hybrids formed by biological entities and human-made nano-structures have been intensively studied in recent years due to their very interesting properties and applications. DNA-carbon nanotube (CNT) hybrid is one such material and the motivation of this PhD study. The interaction of DNA building...
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Spring 2022
The DNA damage response (DDR) is critical for maintaining genomic integrity and prevention of genotoxic consequences leading to carcinogenesis. The DDR signaling cascade results either in the activation of the repair pathway, or initiation of apoptosis if the repair is not possible. Many...
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Fall 2014
Electrons, the fundamental charge carriers in solid-state devices, possess three intrinsic properties: mass, charge and spin. Spin is a quantum mechanical property, but can be loosely visualized as a tiny “intrinsic” magnetic dipole moment attached to an electron. In conventional electron...
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Fall 2014
The assembly of nanoparticle building blocks into more complex nanostructures has important applications in analytical chemistry, materials science, medical science, optics, and electronics. Due to its exquisite specificity and programmable nature, DNA has emerged as a very promising biomolecule...
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The Influence of Specific Ions and System Architecture on the Recognition and Reactivity of Two Charged Materials: DNA-Modified Gold Nanoparticle Aggregates and Planar Silica
DownloadFall 2014
DNA functionalized gold nanoparticles (GNP–DNA) offer simple colorimetric nucleic acid sensing with high selectivity and sensitivity. Consequently, they are promising in genetic profiling, disease diagnostics, and forensic applications. In the presence of a target nucleic acid, GNP–DNA forms...
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Spring 2024
DNA double-strand breaks (DSBs) are considered the most deleterious DNA lesions. Unrepaired or incorrectly repaired DSBs can lead to cell cycle arrest, apoptosis, or over time, the accumulation of mutations and chromosomal abnormalities that give rise to cancer. The repair of DSBs by homologous...
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Fall 2014
Developing a simple, general, and isothermal self-replicating system is one of the key requirements for a simplified detection platform for nucleic acid sequences specific to a disease causing microrganism. One of the challenges in achieving nucleic-acid templated isothermal amplification is that...