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Skip to Search Results- 16Graduate and Postdoctoral Studies (GPS), Faculty of
- 16Graduate and Postdoctoral Studies (GPS), Faculty of/Theses and Dissertations
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International Comparison of Time to Treatment Intensification and Rates of Complications in Metformin Monotherapy Treated Type 2 Diabetes Patients
DownloadFall 2018
Type 2 diabetes mellitus is a progressive disease which affects many people in Canada and the United States, and the prevalence of type 2 diabetes is only expected to increase in the future. Pharmacological interventions are a cornerstone of the management of type 2 diabetes as they help to...
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Landscape Ecology of Mule Deer (Odocoileus hemionus) and White-tailed Deer (O. virginianus) with Implications for Chronic Wasting Disease
DownloadFall 2012
Chronic wasting disease (CWD) is a fatal prion disease of cervids that continues to spread into new regions of Canada despite containment efforts. I examine the importance of landscape connectivity using circuit theory and source/sink habitats that are based on selection, survival and...
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Mapping of genomic regions associated with agronomic traits and resistance to diseases in Canadian spring wheat
DownloadSpring 2017
Wheat breeders, in addition to phenotypic selection, employ molecular markers in their programs for different purposes, including parental selection, quality control, analysis of advanced lines (cultivars), on genetic purity and identity, and for markers assisted selection. In the first study of...
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Middle-Aged and Older Adult Walking and Hiking Groups of Cochrane, Alberta: How Outdoor Group Exercise Influences Perceptions of Health, Healing, and Disease
DownloadFall 2011
Middle-aged and older adult walking and hiking groups of Cochrane had unique perceptions of health and healing due to their activities, the equipment they used, the environments they explored, and the relationships they developed. Past anthropological research has focused on aging, ethnomedicine,...
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Multilocus sequence typing analysis of Clostridium perfringens isolates from necrotic enteritis outbreaks in broiler chickens
Download2008
Jiang, Y. F., Hunter, D. B., Parreira, V. R., Bruce, H. L., Kulkarni, R. R., Prescott, J. F., Chalmers, G., Boerlin, P.
Clostridium perfringens is an important pathogen of animals and humans and is the causative agent of necrotic enteritis (NE) in poultry. This study focuses on the typing of intestinal C. perfringens isolates (n 61) from outbreaks of NE collected from several areas of Southern Ontario, using a...
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Pathologic Evaluation of Type 2 PorcineReproductive and Respiratory SyndromeVirus Infection at the Maternal-FetalInterface of Late Gestation Pregnant Gilts
Download2016-03-10
Novakovic, Predrag, Harding, John C. S., Al-Dissi, Ahmad, Ladinig, Andrea, Detmer, Susan E.
The pathogenesis of fetal death caused by porcine reproductive and respiratory syndromevirus (PRRSV) remains unclear. The objective of this study was to improve our understand-ing of the pathogenesis by assessing potential relationships between specific histopatho-logical lesions and PRRSV RNA...
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2009
Pretorius, V., Majumdar, S.R., McAlister, F.A., Ross, D.B., Norris, C.M., Kapoor, A.S., Mohamed, R.
Background. It has been suggested that the routine use of statins preoperatively would reduce the risk of postoperative infection. We conducted this study to explore whether preoperative statin use was associated with infection after cardiac surgery (recipients of which have a higher-than-average...
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Spring 2011
Technological advances for treatment of congenital heart disease (CHD) have led to decreases in mortality over the past thirty years. Persistent morbidity into adolescence and adulthood necessitates regular medical follow-up and the influence of ongoing physical health issues on the teens...
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The application of computer simulation to investigate drug absorption and bioavailability in disease states
DownloadFall 2015
Oral drug absorption relies mainly on the physicochemical drug properties and the interaction with the physiological environment of the body. These factors could be altered significantly under abnormal conditions and disease states. Identifying these changes can optimize drug therapy under these...