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Skip to Search Results- 1Acedo, Jeella Z
- 1Cochrane, Stephen A.
- 1Drall, Kelsea Michelle
- 1Ho, Linda
- 1Hofstetter, Simmon C
- 1Li, Lin
- 4Department of Chemistry
- 3Department of Agricultural, Food, and Nutritional Science
- 2Department of Chemical and Materials Engineering
- 1Department of Biomedical Engineering
- 1Department of Chemical and Materials Engineering, Medical Sciences - Biomedical Engineering
- 1Medical Sciences-Paediatrics
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Spring 2010
Although nanocrystalline silver is used commercially to treat burns and wounds, the mechanisms of action (MOA) for its activity are not clear. The purposes of this work were to determine if nanocrystalline silver has anti-inflammatory activity, determine physicochemical properties critical for...
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Synthesis and biological evaluation of the lantibiotic peptide lactocin S and its analogues
DownloadSpring 2012
Lantibiotics (lanthionine containing antibiotics) are highly post-translationally modified peptides used by bacteria as a form of chemical warfare. In light of the challenges faced today in the field of antibacterial therapy, these potent natural products are useful lead compounds for the...
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Resistance and Membrane Fluidity of Endospores of Clostridium spp. During Pressure-Assisted Thermal Processing in the Presence of Antimicrobials
DownloadSpring 2012
Endospores of Clostridium spp. pose an economic threat to the food industry and put consumers at risk of foodborne illness. An increase in consumer demand for minimally-processed, ready-to-eat products has driven research to examine ways to mitigate current thermal processing severity used to...
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Application of antimicrobials for the elimination of Escherichia coli and Listeria monocytogenes in brine injected beef
DownloadFall 2013
The application of antimicrobials to a brine-injected raw beef roast for the elimination/inhibition of heat resistant Escherichia coli and Listeria monocytogenes was investigated. The choice of antimicrobials for use in brine injected beef was based on minimum bactericidal concentration in brine...
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Fall 2014
Paenibacillus polymyxa NRRL B-30509, Paenibacillus terrae NRRL B-30644 and P. polymyxa NRRL B-30507 were found to produce several bacteriocins and non-ribosomal peptides. All three strains produce tridecaptins, non-ribosomal lipopeptides antimicrobially active against food pathogen Campylobacter...
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Fall 2016
“Blown-pack” spoilage of beef by psychrotrophic Clostridium spp. occurs sporadically and resistance of the endospores to most interventions makes them very difficult to control. Current interventions used to control spoilage and pathogenic bacteria, such as acid washes and heat treatments, do...
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Spring 2016
The lipopeptides, tridecaptin A1, tridecaptin B1 and cerexin A1 were isolated from Paenibacillus terrae NRRL B-30644, Paenibacillus polymyxa NRRL B-30507 and Bacillus mycoides ATCC 21929, respectively. A combination of chemical synthesis, peptide derivatization, high performance liquid...
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Spring 2017
Mussels can obtain strong underwater attachment to virtually all kinds of surfaces including rocks, metals, wood structures, polymers and concretes by secreting mussel foot proteins to form byssus. Great efforts have been dedicated to understanding this behavior and it is found that an catecholic...
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Spring 2018
Acidocin B (AcdB), a bacteriocin from Lactobacillus acidophilus M46 that was initially reported to be a linear peptide, was purified and shown to be circular based on MALDI-TOF MS and MS/MS sequencing. MS analysis further revealed that AcdB is comprised of 58 amino acid residues, instead of 59...
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Understanding the role of Clostridioides difficile and Vitamin D supplementation in shaping the gut microbiome of Canadian infants
DownloadSpring 2019
Introduction: The gut microbiome is shaped during infancy and has an important role in the development of both the immune and metabolic systems. Many early life exposures and events contribute to the composition of this complex intestinal environment, notably early infant diet and breastfeeding....