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2001-06-01

Hegele, Robert A., Huff, Murray W., Young, T. Kue

"We discovered that rare mutations in LMNA, which encodes lamins A and C, underlie autosomal dominant Dunnigan-type familial partial lipodystrophy. Because familial partial lipodystrophy is an extreme example of genetically disturbed adipocyte differentiation, it is possible that common variation...

2014

Sword, W., Ohinmaa, A., Lasiuk, G., Giallo, R., Kingston, D., van Zanten, S., Biringer, A., Austin, M., Hegadoren, K., Lane-Smith, M., McDonald, S., MacQueen, G.

Background Stress, depression, and anxiety affect 15% to 25% of pregnant women. However, substantial barriers to psychosocial assessment exist, resulting in less than 20% of prenatal care providers assessing and treating mental health problems. Moreover, pregnant women are often reluctant to...

2008

Brennand, Erin A., Vallianatos, Helen, Dannenbaum, David, Petawabano, Beatrice, Raine, Kim, Willows, Noreen D., Stephen, Queenie

Obesity is prevalent among the First Nations population in Canada, with serious associated health risks. Recent studies also indicate that a high percentage of First Nations women are overweight or obese at the start of their pregnancies, with a tendency to retain weight after their children are...

Spring 2012

Gombos, Randi B

Human cytomegalovirus (HCMV) is implicated in several vascular diseases through endothelial dysfunction. Most of the research on CMV has focused on either congenital CMV infections or CMV disease in immunocompromised hosts; however, CMV has also been associated with vascular diseases in...

Spring 2011

Merchant, Neelam

The focus of this study is to understand why, despite high uptake of antenatal care, women in Uganda continue to deliver without skilled birth attendants. A critical gap in our knowledge is an understanding of the decisions women make during pregnancy and childbirth that determine the services...

Fall 2011

Kuhle, Stefan

The prevalence of childhood obesity has increased dramatically over the last three decades in Canada with substantial consequences for the physical, mental, and economic wellbeing of the population. The overarching objective of this thesis was to examine the various aspects of childhood obesity...

Fall 2019

Kebbe, Maryam

Background. Given adolescents’ increasing desire for independence and autonomy, there is a need for research to examine their lived experiences, including concerns, preferences, and priorities. In the context of lifestyle modification for weight management, most adolescents with obesity exhibit...

Fall 2014

Pravdivyi, Igor

An individual’s body weight is tightly regulated by balancing food intake with energy expenditure. This is accomplished in part by secretion of the hormone leptin by adipocytes, an excess of which signals to reduce appetite and increase activity through action in the hypothalamic region of the...

2012-09-18

Zienczuk, Natalia, Young, T. Kue, Cao, Zhirong R., Egeland, Grace M.

"Background: The study’s objective was to investigate the dietary correlates of an at-risk body mass index (BMI) among Inuit adults from thirty-six communities across the Canadian Arctic using data from the cross-sectional International Polar Year Inuit Health Survey, conducted in 2007–2008....

Fall 2020

Brown, Jasmine M.

This dissertation explores the questions “What technology-based interventions are of most benefit in supporting the health and/or rehabilitation of individuals with substance use disorders? Where and how can they be most effectively embedded in the health system?” Chapter 1 begins with an...