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2001

Schaeffer, Jonathan, Charter, K., Lu, Paul, Szafron, Duane, Parsons, I., Driga, A.

Technical report TR01-10. For two DNA or protein sequences of length m and n, dynamic programming alignment algorithms like Needleman-Wunsch and Smith-Waterman take O(m x n) time and use O(m x n) space, so we refer to them as full matrix (FM) algorithms. This space requirement means that large...

Spring 2010

Koziel, Susan P.

Industrial hemp (Cannabis sativa) is a highly productive crop that is well suited to cultivation in Canada. To better understand the development of bast (phloem) fiber secondary walls and to facilitate reverse genetics screening for improved germplasm, I undertook two sets of microarray...

2003-05-13

Wen, Xiao-Yan, Hegele, Robert A., Wang, Jian, Wang, Ding Yan, Cheung, Joseph, Wilson, Michael, Yahyapour, Maryam, Bai, Yahong, Zhuang, Lihua, Skaug, Jennifer, Young, T. Kue, Connelly, Philip W., Koop, Ben F., Tsui, Lap-Chee, Stewart, A. Keith

"Triglyceride (TG) metabolism is crucial for whole body and local energy homeostasis and accumulating evidence suggests an independent association between plasma TG concentration and increased atherosclerosis risk. We previously generated a mouse insertional mutation lpd (lipid defect) whose...

2016

Chen, Tai Y., Foxcroft, George R., Blanes, Milena, Dyck, Michael K., Athorn, Rebecca, Langendijk, Piete, Tsoi, Stephen

The aim of commercial pig breeding programs is to maximize the number of pigs produced per sow per year. Given that sows exhibit an estrus during lactation is a potential means of increasing productivity of a pig breeding herd without reducing in lactation length, conventionally, weaning of...

Fall 2014

Liu, Xiaoji

The growth of Listeria monocytogenes and spoilage microorganisms is a concern in sodium-reduced ready-to-eat (RTE) meats. To assess the microbial risk of sodium-reduced RTE meats, the microbiota of retail RTE meats was profiled and the growth of L. monocytogenes and an autochthonous microbiota...

Fall 2018

Jing, Anqi

Changes in gene expression have been thought to play a crucial role in various types of cancer. With the advance of high-throughput experimental techniques, many genome-wide studies are underway to analyze underlying mechanisms that may drive the changes in gene expression. It has been observed...

Fall 2017

Badr, Dina EFA

The two types of rejection identified in the Banff histopathologic diagnosis are T cell-mediated rejection (TCMR) and antibody-mediated rejection (ABMR). TCMR is most common early post-transplant while ABMR is the main cause of late graft loss. Kidney transplant TCMR is diagnosed histologically...

Spring 2024

Bandi Kenari, Nahid

In this thesis project, three studies were conducted, aimed at identifying the causal variants responsible for phenotypic/genotypic sex discordance in cattle, copper toxicosis in Dalmatian dogs, and low fertility/infertility in cattle. In all three studies, whole-genome sequencing (WGS) and...

2014

Serpe, Michael J., Zhang, Qiang M., Li, Xue, Islam, Molla R., Wei, Menglian

4,40 -Di(acrylamido)-azobenzene was used as a crosslinker in poly(Nisopropylacrylamide)-based microgels. The microgels were subsequently used to fabricate microgel-based optical materials (etalons), which exhibited optical properties that were switchable upon exposure to UV irradiation. We also...

2011

Williams, John L., Moore, Stephen S., Almeida, Luciane M., Basu, Urmila, Guan, Leluo

Bovine spongiform encephalopathy (BSE) is a fatal disorder in cattle characterized by progressive neurodegeneration of the central nervous system. We investigated the molecular mechanisms involved in neurodegeneration during prion infection through the identification of genes that are...