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Skip to Search Results- 10Kitova, Elena N.
- 10Klassen, John S.
- 2Cairo, Christopher W.
- 2Darestani, Reza R.
- 2Eugenio, Luiz
- 2Fan, Xuxin
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1994
Wright, G.E., Reha-Krantz, L.J., Khan, N.N.
Bacteriophage T4 DNA polymerase was Inhibited by butylphenyl nucleotldes, aphldlcolin and pyrophosphate analogs, but with lower sensitivities than other members of the B family DNA polymerases. The nucleotides N2-{p-n-butylphenyl)dGTP (BuPdGTP) and 2-{p-n-butylanilino)dATP (BuAdATP) inhibited T4...
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2016
Klassen, John S., Han, Ling, Kitova, Elena N.
This study reports on the use of the catch-and-release electrospray ionization mass spectrometry (CaR-ESI-MS) assay, combined with glycomicelles, as a method for detecting specific interactions between water-soluble proteins and glycolipids (GLs) in aqueous solution. The B subunit homopentamers...
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2016
Han, Ling, Klassen, John S., Kitova, Elena N.
This study reports on the use of the catch-and-release electrospray ionization mass spectrometry (CaR-ESI-MS) assay, combined with glycomicelles, as a method for detecting specific interactions between water-soluble proteins and glycolipids (GLs) in aqueous solution. The B subunit homopentamers...
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2012
Klassen, John S., Lin, Hong, Kitova, Elena N., Ng, Kenneth K., Johnson, M. A., Eugenio, Luiz
Electrospray ionization mass spectrometry (ESI-MS) measurements were performed under a variety of solution conditions on a highly acidic sub-fragment (B3C) of the C-terminal carbohydrate-binding repeat region of Clostridium difficile toxin B, and two mutants (B4A and B4B) containing fewer acidic...
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2012
Klassen, John S., Lin, Hong, Kitova, Elena N., Ng, Kenneth K., Johnson, M. A., Eugenio, Luiz
Electrospray ionization mass spectrometry (ESI-MS) measurements were performed under a variety of solution conditions on a highly acidic sub-fragment (B3C) of the C-terminal carbohydrate-binding repeat region of Clostridium difficile toxin B, and two mutants (B4A and B4B) containing fewer acidic...
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Gene structure of the goldfish agouti-signaling protein: A putative role in the dorsal-ventral pigment pattern of fish
Download2005
Schioth, H.B., Haitina, T., Cerdá-Reverter, J.M., Peter, R.E.
One of the most successful chromatic adaptations in vertebrates is the dorsal-ventral pigment pattern in which the dorsal skin is darkly colored, whereas the ventrum is light. In fish, the latter pattern is achieved because a melanization inhibition factor inhibits melanoblast differentiation and...
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2007
Wang, W., Wang, H., Wong, G.K.S., Zheng, H., Clark, T., Zhang, G., Kang, L., Wang, J., Shi, J., Wang, X.
Background Insects constitute the vast majority of known species with their importance including biodiversity, agricultural, and human health concerns. It is likely that the successful adaptation of the Insecta clade depends on specific components in its proteome that give rise to specialized...
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Nonspecific interactions between proteins and charged biomolecules in electrospray ionization mass spectrometry
Download2010
Soya, Naoto, Klassen, John S., Kitova, Elena N., Sun, Nian
An investigation of the nonspecific association of small charged biomolecules and proteins in electrospray ionization mass spectrometry (ES-MS) is described. Aqueous solutions containing pairs of proteins and a small acidic or basic biomolecule that does not interact specifically with either of...
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Nonspecific interactions between proteins and charged biomolecules in electrospray ionization mass spectrometry
Download2010
Kitova, Elena N., Sun, Nian, Klassen, John S., Soya, Naoto
An investigation of the nonspecific association of small charged biomolecules and proteins in electrospray ionization mass spectrometry (ES-MS) is described. Aqueous solutions containing pairs of proteins and a small acidic or basic biomolecule that does not interact specifically with either of...
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Screening anti-cancer drugs against tubulin using catch-and-release electrospray ionization mass spectrometry
Download2016
Kitova, Elena N., Klassen, John S., Winter, Philip, Tuszynski, Jack A., Darestani, Reza R.
Tubulin, which is the building block of microtubules, plays an important role in cell division. This critical role makes tubulin an attractive target for the development of chemotherapeutic drugs to treat cancer. Currently, there is no general binding assay for tubulin–drug interactions. The...