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Skip to Search Results- 8University of Alberta, Department of Biological Sciences
- 1 Li, Jun
- 1Abd Elhafiz, Areeg
- 1Abeysundara, Namal W
- 1Anderson-Baron, Matthew N
- 1Androschuk, Alaura MA
- 28Graduate and Postdoctoral Studies (GPS), Faculty of
- 28Graduate and Postdoctoral Studies (GPS), Faculty of/Theses and Dissertations
- 12Biological Sciences, Department of
- 8Biological Sciences, Department of/BioSci OER
- 4Biological Sciences, Department of/Journal Articles (Biological Sciences)
- 1Roy Berg Kinsella Research Ranch
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Fall 2020
Peroxisomes are organelles responsible for processing lipids and managing reactive oxygen species. A conserved family of genes called peroxisome biogenesis factors (Peroxin, Pex) encode proteins necessary for peroxisome biogenesis and function. In yeast and mammals, PEROXIN7 (PEX7) acts as a...
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2005-09-01
Samudrala, Ram , Zheng, Hongkun , Li, Jun, Yang, Shuang , Zhang, Jianguo , Yu, Haijing , McDermott, Jason , Wang, Wen , Yang, Huanming , Jiang, Huifeng , Yang, Lei , Wang, Jian , Wong, Gane K., Kristiansen, Karsten , Su, Jianning , Yu, Jun
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Spring 2019
Organelles serve to compartmentalize biochemical functions within the eukaryotic cell. However, to collectively maintain cellular homeostasis, organelles must communicate in some way in order to coordinate these functions. Two such organelles,the peroxisome and the lipid droplet, are both...
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Proliferative Signals Regulate Hemocyte Development and Intestinal Immunity in Drosophila melanogaster.
DownloadSpring 2015
The innate immune system is an ancient line of resistance against intrusive microbial threats. This system integrates cellular, humoral, and barrier defenses to generate a protective immune response. These divisions are indispensable and conserved between Drosophila and mammals. Hemocytes are the...
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Regulation of digestive tract and progenitor cell homeostasis by intestinal bacteria in Drosophila melanogaster
DownloadFall 2020
The digestive tract facilitates nutrient uptake in the presence of a heterogenous cohort of symbiotic microbes. These microbes along with their collective genetic material form the intestinal microbiome and contribute to animal phenotypes. Similar to mammals, the microbiome of insects forms a...
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Spring 2010
Development of the vertebrate central nervous system is a complex process that relies on the accurate spatiotemporal distribution of signaling centers during embryogenesis. These signals provide cells with positional information, which is integrated via transcription factors and gene regulatory...
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Spring 2013
The innate immune system is an evolutionarily conserved first line of defense against invasive microbes. Studies in the fruit fly, Drosophila melanogaster, revolutionized the field of immunology and cemented Drosophila as a premier model of innate immune defenses. The Drosophila immune deficiency...
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The roles of vestigial and scalloped in the embryonic muscle development of Drosophila melanogaster
DownloadFall 2010
Vertebrate development requires the activity of multiple members of the myocyte enhancer factor 2 (mef2) gene family for muscle cell specification and subsequent differentiation. Additionally, it is thought that several muscle-specific functions of MEF2 family proteins require binding additional...
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The Study of Hereditary Spastic Paraplegia Genes Using Drosophila Homologues: Behavioural Insights
DownloadFall 2014
Hereditary Spastic Paraplegia (HSP) denotes a heterogeneous group of heritable neurodegenerative disorders predominantly characterized by progressive weakness and spasticity of the legs. Mutations in the gene SPAST are by far the most common, while mutations in the gene ATL1 are the second most...
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Fall 2014
Fragile X Syndrome (FXS) is the most common genetic cause of Intellectual Disability, affecting 1 in 4000 boys and 1 in 6000 girls. Work in our lab using Drosophila melanogaster and since replicated in the mouse model has shown that excess protein synthesis is a major mechanism connecting the...