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Skip to Search Results- 1El-Kadi, Ayman (Faculty of Pharmacy and Pharmaceutical Sciences)
- 1Kamaljit Kaur (Faculty of Pharmacy and Pharmaceutical Sciences)
- 1Kaur, Kamaljit (Faculty of Pharmacy and Pharmaceutical Sciences)
- 1Loebenberg, Raimar (Pharmaceutical Sciences)
- 1Roa, Wilson (Department of Oncology)
- 1Siraki, Arno (Pharmaceutical Sciences)
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Fall 2010
The purpose of this project was to formulate, modify and evaluate nanoparticles for targeting asialoglycoprotein receptor found in large numbers exclusively on hepatocyte surfaces. Our goal is to increase the efficacy, reduce the side effects and the cost of the hydrophilic drugs administered to...
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Fall 2012
Dendritic cells (DCs) play a central role in shaping antigen-specific immune response. Antibody-mediated antigen targeting to DC-specific surface receptors is a promising approach to enhance vaccine efficacy. The objective of this thesis was to develop DC-targeted nanoparticulate formulations for...
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MODULATION OF ARYL HYDROCARBON RECEPTOR (AHR)-REGULATED CARCINOGEN ACTIVATING ENZYMES BY ORGANIC ARSENICALS: A POTENTIAL THERAPEUTIC TARGET
DownloadSpring 2017
Arsenic is a worldwide environmental pollutant that is associated with skin and several types of internal cancers, such as liver, lung, kidney, urinary bladder, and prostate cancers. Recent reports revealed that organic arsenic metabolites, such as trimethylarsine oxide (TMAO), dimethylarsinic...
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Fall 2016
Macrophages are the primary cells of innate immunity that provide the first line of defence against any external stimuli. Their phagocytic properties enable them to engulf invading microbes or foreign particles. The phagocytic capability of macrophages plays a major role in interfering with drug...