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Skip to Search Results- 2Finlay, Warren H.
- 2Löbenberg, Raimar
- 1Al-Hallak, M. H. D. Kamal
- 1Arshad, Muhammad
- 1Azarmi, Shirzad
- 1Bachynsky, J.
- 20Graduate and Postdoctoral Studies (GPS), Faculty of
- 20Graduate and Postdoctoral Studies (GPS), Faculty of /Theses and Dissertations
- 3Pharmacy and Pharmaceutical Sciences, Faculty of
- 3Pharmacy and Pharmaceutical Sciences, Faculty of/Journal Articles (Pharmacy and Pharmaceutical Sciences)
- 1Renewable Resources, Department of
- 1Renewable Resources, Department of/Conference Proceedings (Renewable Resources)
- 4Department of Chemical and Materials Engineering
- 4Department of Chemistry
- 3Department of Renewable Resources
- 2Department of Physiology
- 2Faculty of Pharmacy and Pharmaceutical Sciences
- 2Medical Sciences-Laboratory Medicine and Pathology
- 2Leslie, Elaine (Physiology)
- 1Dr. Afsaneh Lavasanifar (Faculty of Pharmacy and Pharmaceutical Sciences)
- 1Dr. Tariq Siddique (Department of Renewable Resources)
- 1El-Kadi, Ayman (Faculty of Pharmacy and Pharmaceutical Sciences)
- 1Hacke, Uwe (Renewable Resources)
- 1Laur, Joan (External - University of Montreal)
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Spring 2016
Arsenic is a proven human carcinogen and associated with a myriad of other adverse health effects. This metalloid is methylated in human liver to monomethylarsonic acid (MMAV), monomethylarsonous acid (MMAIII), dimethylarsinic acid (DMAV), and dimethylarsinous acid (DMAIII) and eliminated...
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MODULATION OF ARYL HYDROCARBON RECEPTOR (AHR)-REGULATED CARCINOGEN ACTIVATING ENZYMES BY ORGANIC ARSENICALS: A POTENTIAL THERAPEUTIC TARGET
DownloadSpring 2017
Arsenic is a worldwide environmental pollutant that is associated with skin and several types of internal cancers, such as liver, lung, kidney, urinary bladder, and prostate cancers. Recent reports revealed that organic arsenic metabolites, such as trimethylarsine oxide (TMAO), dimethylarsinic...
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Nanodelivery of Novel Inhibitors of ERCC1/XPF for sensitizing colorectal cancer cell to platinum drugs
DownloadSpring 2023
This project's long-term goal is to increase the efficacy of genotoxic therapeutics through thesensitization of cells to DNA-damaging therapy ahead of the treatment. The focus of this projectwas on the enhancement of platinum-based chemotherapeutics in colorectal cancer usingcolorectal cancer...
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Natural and anthropogenic inputs of arsenic and selenium to the environment in the Athabasca Bituminous Sands Region
DownloadSpring 2019
Industrial development of the Athabasca Bituminous Sands (ABS) in northern Alberta, Canada, has raised concerns that emissions of arsenic and selenium to the surrounding landscape and waterbodies have been increasing over time. To test this hypothesis, a comprehensive study of arsenic and...
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Spring 2012
The present thesis describes preliminary studies required for evaluating silicon nanocrystals (Si-NCs) as photothermal (PT) therapy agents and drug delivery vehicles. Group 14 semiconductor NCs are of particular interest for these applications because of their tailorable optical response and...
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Poly n-butylcyanoacrylate (PNBCA) nanocapsules as a carrier for NSAIDs: in vitro release and in vivo skin penetration
Download2003
Kubo, W., Takahashi, A., Miyazaki, S., Löbenberg, R., Bachynsky, J.
Abstract: Purpose: The aim of this work was to prepare poly n-butylcyanoacrylate (PNBCA) nanocapsules loaded with indomethacin and to evaluate the ability of this carrier system to deliver the drug systemically after its topical application. Methods: Poly n-butylcyanoacrylate (PNBCA) nanocapsules...
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Risk estimates of arsenic related skin lesions in two large villages in Rajshahi Division, Bangladesh
DownloadFall 2009
In rural Bangladesh people drink water from an estimated 10-11 million tube wells, many with arsenic concentrations well above the national standard of 50µg/L. Characteristic skin lesions and more serious health effects are probable. The research reported here was designed to determine the...