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Skip to Search Results- 17Graduate and Postdoctoral Studies (GPS), Faculty of
- 17Graduate and Postdoctoral Studies (GPS), Faculty of/Theses and Dissertations
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- 2Roy Berg Kinsella Research Ranch
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Fall 2010
Mast cells are immune cells important in innate immunity. Besides their role in asthma and allergies, mast cells are critical effector cells against various pathogens. Mast cells are established to be protective against bacterial infections, but little is known about their functions in viral...
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Fall 2017
Most antivirals target viral proteins and are specific for only one virus, or even one viral genotype. Whereas viral proteins are encoded in the plastic viral genome, virion lipids are not and their rearrangements during fusion of the virion envelope to cellular membranes are conserved among...
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Application of Next Generation Sequencing and Bioinformatic Approaches to the Study of Influenza Virus Strains and MiRNA Profiling in Liver Diseases
DownloadSpring 2016
Analysis and interpretation of next generation sequencing data has posed a significant challenge to researchers, especially to those who are not equipped with expertise in bioinformatics. In this thesis, I investigated three different biomedical questions using NGS and bioinformatic approaches,...
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Chapter 5 Supplement A: Included and Excluded Studies
2012-08-17
Chapter 5, Supplement A of a doctoral dissertation (Lau, D. Diabetes and Influenza-Attributable Illness: The Rationale for Targeted Influenza Vaccinations in Adults with Diabetes. Edmonton, AB: University of Alberta, Fall 2012). This supplement contains certain methodological details, as well as...
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Chapter 5 Supplement B: Meta-Analyses of Quality Improvement Interventions – Influenza Vaccinations
Chapter 5 Supplement B: Meta-Analyses of Quality Improvement Interventions – Influenza Vaccinations
Download2012-08-17
Chapter 5, Supplement B of a doctoral dissertation (Lau, D. Diabetes and Influenza-Attributable Illness: The Rationale for Targeted Influenza Vaccinations in Adults with Diabetes. Edmonton, AB: University of Alberta, Fall 2012). This supplement contains forest plots from meta-analyses of...
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Chapter 5 Supplement C: Meta-Analyses of Quality Improvement Interventions – Pneumococcal Vaccinations
Chapter 5 Supplement C: Meta-Analyses of Quality Improvement Interventions – Pneumococcal Vaccinations
Download2012-08-17
Chapter 5, Supplement C of a doctoral dissertation (Lau, D. Diabetes and Influenza-Attributable Illness: The Rationale for Targeted Influenza Vaccinations in Adults with Diabetes. Edmonton, AB: University of Alberta, Fall 2012). This supplement contains forest plots from meta-analyses of...
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Chapter 5 Supplement D: Sub-Stratified Quality Improvement Interventions and Numbers Needed to Treat
Chapter 5 Supplement D: Sub-Stratified Quality Improvement Interventions and Numbers Needed to Treat
Download2012-08-17
Chapter 5, Supplement D of a doctoral dissertation (Lau, D. Diabetes and Influenza-Attributable Illness: The Rationale for Targeted Influenza Vaccinations in Adults with Diabetes. Edmonton, AB: University of Alberta, Fall 2012). This supplement contains additional figures and tables from data...
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Characterizing the effects of differentially adapted influenza PB2 proteins on duck MAVS-mediated interferon beta signaling
DownloadFall 2015
The influenza A viral RNA polymerase is responsible for viral replication and greatly affects influenza A virus (IAV) virulence and host range. The PB2 influenza polymerase subunit is the primary polymerase determinant of influenza host range and virulence. It was previously shown that PB2...
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Cytokine profiles in pregnant gilts experimentally infected with porcine reproductive and respiratory syndrome virus and relationships with viral load and fetal outcome
Download2014
Plastow, G., Souza, C. J. H., Lunney, J. K., Ashley, C., Ladinig, A., Harding, J. C. S.
In spite of extensive research, immunologic control mechanisms against Porcine Reproductive and Respiratory Syndrome virus (PRRSv) remain poorly understood. Cytokine responses have been exhaustively studied in nursery pigs and show contradictory results. Since no detailed reports on cytokine...
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Development of Oral Influenza Vaccine Delivery System Utilizing pH Responsive Pored Microparticles
DownloadFall 2015
Influenza is a major respiratory disease caused by influenza virus. Recent spread of the extremely pathogenic avian and swine influenza viruses paint a morbid picture of the emergence of a more lethal influenza virus in future. Currently, hypodermic needles are being dominantly employed in...