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Skip to Search Results- 22Graduate and Postdoctoral Studies (GPS), Faculty of
- 22Graduate and Postdoctoral Studies (GPS), Faculty of/Theses and Dissertations
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A large deletion virus reveals the presence of previously uncharacterized vaccinia virus inhibitors of NF-kB signaling
DownloadFall 2010
The classical Nuclear Factor kappa B (NF-κB) signaling pathway is an important regulator of inflammation and innate immune responses. Poxviruses, including vaccinia virus, encode multiple immune evasion proteins, including a growing number of NF-κB inhibitors. To determine if additional vaccinia...
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Fall 2010
Mast cells are immune cells important in innate immunity. Besides their role in asthma and allergies, mast cells are critical effector cells against various pathogens. Mast cells are established to be protective against bacterial infections, but little is known about their functions in viral...
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Fall 2017
Most antivirals target viral proteins and are specific for only one virus, or even one viral genotype. Whereas viral proteins are encoded in the plastic viral genome, virion lipids are not and their rearrangements during fusion of the virion envelope to cellular membranes are conserved among...
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Application of Next Generation Sequencing and Bioinformatic Approaches to the Study of Influenza Virus Strains and MiRNA Profiling in Liver Diseases
DownloadSpring 2016
Analysis and interpretation of next generation sequencing data has posed a significant challenge to researchers, especially to those who are not equipped with expertise in bioinformatics. In this thesis, I investigated three different biomedical questions using NGS and bioinformatic approaches,...
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Chapter 5 Supplement A: Included and Excluded Studies
2012-08-17
Chapter 5, Supplement A of a doctoral dissertation (Lau, D. Diabetes and Influenza-Attributable Illness: The Rationale for Targeted Influenza Vaccinations in Adults with Diabetes. Edmonton, AB: University of Alberta, Fall 2012). This supplement contains certain methodological details, as well as...
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Chapter 5 Supplement B: Meta-Analyses of Quality Improvement Interventions – Influenza Vaccinations
Chapter 5 Supplement B: Meta-Analyses of Quality Improvement Interventions – Influenza Vaccinations
Download2012-08-17
Chapter 5, Supplement B of a doctoral dissertation (Lau, D. Diabetes and Influenza-Attributable Illness: The Rationale for Targeted Influenza Vaccinations in Adults with Diabetes. Edmonton, AB: University of Alberta, Fall 2012). This supplement contains forest plots from meta-analyses of...
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Chapter 5 Supplement C: Meta-Analyses of Quality Improvement Interventions – Pneumococcal Vaccinations
Chapter 5 Supplement C: Meta-Analyses of Quality Improvement Interventions – Pneumococcal Vaccinations
Download2012-08-17
Chapter 5, Supplement C of a doctoral dissertation (Lau, D. Diabetes and Influenza-Attributable Illness: The Rationale for Targeted Influenza Vaccinations in Adults with Diabetes. Edmonton, AB: University of Alberta, Fall 2012). This supplement contains forest plots from meta-analyses of...
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Chapter 5 Supplement D: Sub-Stratified Quality Improvement Interventions and Numbers Needed to Treat
Chapter 5 Supplement D: Sub-Stratified Quality Improvement Interventions and Numbers Needed to Treat
Download2012-08-17
Chapter 5, Supplement D of a doctoral dissertation (Lau, D. Diabetes and Influenza-Attributable Illness: The Rationale for Targeted Influenza Vaccinations in Adults with Diabetes. Edmonton, AB: University of Alberta, Fall 2012). This supplement contains additional figures and tables from data...
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Spring 2014
The introduction of WNV into North America in 1999 was followed by rapid spread throughout the continent. Today, WNV is an endemic pathogen in the west, with thousands of cases of severe infection reported annually. In addition to traditional vaccine research, there is an urgent need to...
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Characterization of the cold stress-induced cyanobacterial DEAD-box protein CrhC as an RNA helicase
Download2000
Owttrim, George W., Yu, Esther
We have shown previously that CrhC is a unique member of the DEAD-box family of RNA helicases whose expression occurs specifically under conditions of cold stress. Here we show that recombinant His-tagged CrhC, purified from Escherichia coli, is an ATP-independent RNA binding protein possessing...