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Skip to Search Results- 1Alanazi, Malik
- 1Denys, Kennedy A
- 1Douglas, Claire
- 1El-Sheikh, Amr.
- 1Elfring, Tracy Tamiko
- 1Gaudet, Wendy Rochelle.
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Fall 2020
Background: A standard treatment option for locally advanced rectal cancer includes 5-6 weeks of neoadjuvant chemoradiation (NACRT) followed by surgery about 6-8 weeks later. NACRT improves outcomes for rectal cancer patients but also causes acute toxicities which may impede quality of life...
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Impact of conventional fractionated RT to pelvic lymph nodes and dose-escalated hypofractionated RT to prostate gland using IMRT treatment delivery in high-risk prostate cancer
DownloadFall 2009
Prostate cancer is the most common cancer among Canadian men. The standard treatment in high-risk category is radical radiation, with androgen suppression treatment (AST). Significant disease progression is reported despite this approach. Radiation dose escalation has been shown to improve...
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Individualized Health Related Quality of Life Measures: their use in children and their psychometric properties
DownloadFall 2012
Health related quality of life (HRQL) has recently been recognized as an essential outcome of patient-centered care. Individualized HRQL (iHRQL) measures propose a patient-centered approach to HRQL measurement; these measures allow patients to nominate areas of life that are important and then...
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Inhibition and enhancement of Respiratory Syncytial Virus replication by nucleoside analogues and bis(indole) compounds
DownloadSpring 2019
Respiratory syncytial virus (RSV) is an Orthopneumovirus that infects the epithelium of the airways. Severe RSV infection of the lower respiratory tract in infants is a leading cause of pediatric hospitalizations. RSV also causes substantial morbidity in immunocompromised and elderly populations....
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Fall 2016
Background: A pilot community-based antiretroviral therapy (CBART) program in western Uganda was previously shown to significantly improve quality of life outcomes among HIV patients in their first year of treatment, though certain psychosocial challenges and issues remained. What is not known...
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Metrology of Health-Related Quality of Life Measurements in Adults and Adolescents with Scoliosis
DownloadFall 2020
Background: Scoliosis impacts Quality of Life (QOL). Stabilization exercises have been shown to be effective for improving patient reported outcomes (PROMS.); however, our literature review examining the effects of such exercises on QOL showed that such studies in adults with scoliosis are...
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Fall 2017
Cancers in the head and neck often lead to disability in basic functions, including speech and swallowing. Restoration of these functional impairments is the main treatment goals in managing patients affected by head and neck cancer. Historically, expert stakeholders including clinicians and...