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Skip to Search Results- 1Beilman, Candace L
- 1Chappell, Kaitlyn
- 1Dai, Jiayi
- 1El-Matary, Wael
- 1El-Sheikh, Amr.
- 1Eslamparast, Tannaz
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The influence of iron therapy on the clinical outcomes, the colonic bacteria microbiome and the urinary metabolomics in iron deficient subjects
DownloadFall 2011
Iron deficiency is a common problem facing subjects with inflammatory bowel disease and it is of recurrent nature. It is associated with lethargy, fatigue and poorer cognition independent of anaemia. These symptoms could be reversed with iron supplementation either via oral or intravenous route....
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The mechanism of action of cidofovir and (S)-9-(3-hydroxy-2-phosphonomethoxypropyl)adenine against viral polymerases
DownloadFall 2009
The nucleoside phosphonates cidofovir (CDV) and (S)-9-[3-hydroxy-(2-phosphonomethoxy)propyl]adenine [(S)-HPMPA] are analogs of dCMP and dAMP, respectively. Collectively these drugs are effective inhibitors of a wide range of DNA viruses, RNA viruses, and retroviruses. Because they are nucleotide...
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The Role of Vitamin D in Anti-Tumor Necrosis Factor-Alpha-Induced Response in Patients with Inflammatory Bowel Disease
DownloadFall 2014
Vitamin D is an important immunomodulator of the immune system and has been suggested to play a role in the pathogenesis of inflammatory bowel disease (IBD). Drugs targeting TNF-alpha are effective IBD therapies, and vitamin D has been demonstrated to suppress TNF-alpha as well as work...
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Spring 2015
The tumor suppressor protein Ras association domain family 1A (RASSF1A) has roles in multiple signaling pathways including modulating apoptosis, the cell cycle, DNA damage, and microtubule organization. RASSF1A has been shown to be one of the most frequently epigenetically silenced genes in a...
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The Validity of Patient-led Self- screens for Identifying Malnutrition in Inflammatory Bowel Disease
DownloadFall 2018
Background: Malnutrition is common in Inflammatory Bowel Disease (IBD) and is associated with significant morbidity and mortality. Identification of high-risk patients using a sensitive and reliable screen is the first step to dietitian referral for nutritional assessment and intervention. Aim:...
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Treatment of Antiviral Drugs in Wastewater Using Advanced Oxidation Processes - Ozonation of Oseltamivir Phosphate
DownloadFall 2021
While wastewater treatment facilities are designed to remove contaminants from water before it returns to the environment, unfortunately, not all of these facilities are effective in the removal of micropollutants (MPs). Antiviral drugs are a class of MPs that have become an area of concern due...