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Skip to Search Results- 1Abbott, D. Wade
- 1Abdulrahman, Nabeel
- 1Barkema, Herman W.
- 1Barnum, D. A.
- 1Bertozzi Silva, Juliano
- 1Boerlin, P.
- 3Agricultural, Food and Nutritional Science, Department of
- 3Agricultural, Food and Nutritional Science, Department of/Journal Articles (Agricultural, Food and Nutritional Science)
- 3Graduate and Postdoctoral Studies (GPS), Faculty of
- 3Graduate and Postdoctoral Studies (GPS), Faculty of/Theses and Dissertations
- 1Biochemistry, Department of
- 1Biochemistry, Department of/Journal Articles (Biochemistry)
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2011
Willing, Benjamin P., Finlay, B. Brett , Thanachayanont, Teerawat, Croxen, Matthew, Vacharaksa, Anjalee
Host resistance to bacterial infections is thought to be dictated by host genetic factors. Infections by the natural murine enteric pathogen Citrobacter rodentium (used as a model of human enteropathogenic and enterohaemorrhagic E. coli infections) vary between mice strains, from mild...
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Antimicrobial Use Surveillance Indicators: Use and Practicality in Salmonid Aquaculture Settings
DownloadFall 2021
Antimicrobial resistance (AMR) is a unique threat to One Health, and salmonid aquaculture industries are increasingly challenged to demonstrate responsible antimicrobial stewardship. Indicators and metrics to quantify antimicrobial use (AMU) data can comparatively enhance understanding of...
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Bacteriophages as antimicrobial agents against bacterial contaminants in yeast fermentation processes
DownloadFall 2013
Bacterial contaminants are ubiquitous in yeast fermentation processes for biofuel production. In general, they compete with yeasts for nutrients, reducing overall production yield. The present project investigates the application of bacteriophages (phages), viruses infecting and killing...
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Comparative variation within the genome of Campylobacter jejuni NCTC 11168 in human and murine hosts
Download2014
Selinger, L. Brent, Taboada, Eduardo N., Uwiera, Richard R. E., Abbott, D. Wade, Inglis, G. Douglas, Thomas, Dallas K., Lone, Abdul G.
Campylobacteriosis incited by C. jejuni is a significant enteric disease of human beings. A person working with two reference strains of C. jejuni National Collection of Type Cultures (NCTC) 11168 developed symptoms of severe enteritis including bloody diarrhea. The worker was determined to be...
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Environmental particulate matter induces murine intestinal inflammatory responses and alters the gut microbiome
Download2013-01-01
Thiesen, Aducio, Rioux, Kevin P., Tso, Robert, Kish, Lisa, Barkema, Herman W., Madsen, Karen L., Vincent, Renaud, Wine, Eytan, Kaplan, Gilaad G., Hotte, Naomi, Gänzle, Michael G.
Background Particulate matter (PM) is a key pollutant in ambient air that has been associated with negative health conditions in urban environments. The aim of this study was to examine the effects of orally administered PM on the gut microbiome and immune function under normal and inflammatory...
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Fall 2017
Strains of Escherichia coli may survive heat or pressure stress, acquire specific virulence genes and cause severe human diseases. The locus of heat resistance (LHR) has been identified as an important heat resistant element in E. coli. The objective of this thesis was to explore the role of the...
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Na+/H+ exchanger isoform 1-induced osteopontin expression facilitates cardiomyocyte hypertrophy
Download2015-01-01
Mohamed, Iman A., Gadeau, Alain-Pierre, Fliegel, Larry, Lopaschuk, Gary, Mlih, Mohamed, Abdulrahman, Nabeel, Filmore, Natasha, Mraiche, Fatima
Enhanced expression and activity of the Na+/H+ exchanger isoform 1 (NHE1) has been implicated in cardiomyocyte hypertrophy in various experimental models. The upregulation of NHE1 was correlated with an increase in osteopontin (OPN) expression in models of cardiac hypertrophy (CH), and the...
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Necrotic enteritis potential in a model system using Clostridium perfringens isolated from field outbreaks
Download2007
Toole, D. L., , Barnum, D. A., Bruce, H. L., Boerlin, P., Chalmers, G.
Necrotic enteritis is an enteric disease of avian species caused by the anaerobic bacterium Clostridium perfringens. The disease is regularly controlled in the broiler chicken industry through the use of antimicrobials in feed, but is re-emerging in areas such as Europe where there is a ban on...