Necrotic enteritis potential in a model system using Clostridium perfringens isolated from field outbreaks

• Author(s) / Creator(s)

  • Toole, D. L.,
  • Barnum, D. A.
  • Bruce, H. L.
  • Boerlin, P.
  • Chalmers, G.

• Necrotic enteritis is an enteric disease of avian species caused by the
  anaerobic bacterium Clostridium perfringens. The disease is regularly
  controlled in the broiler chicken industry through the use of
  antimicrobials in feed, but is re-emerging in areas such as Europe
  where there is a ban on antimicrobials as growth promoters. In order to
  study prospective therapies, researchers must be able to reproduce this
  disease in a controlled environment, but this is not always possible due
  to differences in the pathogenicity of C. perfringens strains. The
  objective of this study was to test the potential of 5 isolates (SNECP43,
  44, 47, 49 and 50), taken from field cases of necrotic enteritis, at
  recreating the disease in a controlled challenge experiment.

• Date created

  2007

• Subjects / Keywords

  • Antimicrobials
  • Broiler chickens
  • Necrotic enteritis

• Type of Item

  Article (Published)

• DOI

  https://doi.org/10.7939/R34F1MK20

• License

  E 2007, American Association of Avian Pathologists, Inc. This is an open access article. The authors must be cited.