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- 2Weselake, Randall J.
- 1Ahmed Samir Ead
- 1Ametaj, Burim N.
- 1Athanassakis-Vassiliadis, Irene
- 1Berke, Sheldon S
- 20Graduate and Postdoctoral Studies (GPS), Faculty of
- 20Graduate and Postdoctoral Studies (GPS), Faculty of/Theses and Dissertations
- 3Agricultural, Food and Nutritional Science, Department of
- 3Agricultural, Food and Nutritional Science, Department of/Journal Articles (Agricultural, Food and Nutritional Science)
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- 2WISEST Summer Research Program/WISEST Research Posters
- 3Department of Agricultural, Food, and Nutritional Science
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- 3Department of Medicine
- 3Department of Oncology
- 2Department of Medical Sciences
- 1Department of Agricultural, Food and Nutritional Science
- 3Deyholos, Michael (Biological Sciences)
- 1Abdulkarim, Bassam (Oncology)
- 1Allan Murray (Medicine)
- 1Ambrose, Divakar (Department of Agricultural, Food and Nutritional Science)
- 1Bell, Rhonda (Department of Agricultural, Food, and Nutritional Science)
- 1Davidge, Sandra T (Obstetrics and Gynecology/ Physiology)
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Fall 2013
Lectins are proteins that bind specifically to carbohydrates and are active in plant defense and other processes. The sequencing of the flax (Linum usitatissimum) genome showed that it was unusually rich in genes predicted to encode one or more agglutinin domains (PFAM PF07468). This domain is...
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Differential responses in placenta and fetal thymus at 12 days post infection elucidate mechanisms of viral level and fetal compromise following PRRSV2 infection
Download2020-01-01
Van Goor, Angelica, Pasternak, Alex, Walker, Kristen, Hong, Linjun, Malgarin, Carolina, MacPhee, Daniel J., Harding, John C. S., Lunney, Joan K.
Background:A pregnant gilt infected with porcine reproductive and respiratory syndrome virus (PRRSV) can transmit the virus to her fetuses across the maternal-fetal-interface resulting in varying disease outcomes. However,the mechanisms leading to variation in fetal outcome in response to PRRSV...
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Fall 2017
Epidermal Growth Factor-like domain 7 (EGFL7) is a secreted angiogenic factor that is almost exclusively expressed by endothelial cells. High EGFL7 expression occurs during physiological angiogenesis, under pathological conditions, and in solid tumor angiogenesis. Evidence suggests that EGFL7...
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Fall 2022
Heart transplantation (HTx) is a life-saving intervention for patients with end-stage heart failure. Nonetheless, the development of Chronic Allograft Vasculopathy (CAV) limits the longevity of transplanted cardiac allografts and the survival of recipients. The pathogenesis of CAV begins with a...
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Exploiting the Enhanced Permeability and Retention Effect for the Targeting of Tumors with 18F-SiFA Polymer Nanoparticles
DownloadFall 2017
Over the last several decades great progress has been made in cancer diagnosis and detection. One foundation of this progress has been improved imaging technologies. Among the most promising imaging technologies for cancer detection is Positron Emission Tomography (PET). PET imaging allows for...
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High fructose intake during pregnancy adversely affects insulin resistance, lipid profiles, and affects placental gene expression of nutrient transporters and angiogenesis in rat dams and their pregnant offspring
DownloadSpring 2017
Fructose intake has increased over the past several decades due to high consumption of sugary foods and drinks. In non-pregnant humans and animals, high fructose intake results in hyperlipidemia, insulin resistance and weight gain, although its effects on metabolic adaptations to pregnancy and on...
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Identification of a pair of phospholipid:diacylglycerol acyltransferases from developing flax (Linum usitatissiumum L.) seed catalyzing the selective production of trilinolenin
Download2013
Wickramarathna, Aruna D., Siloto, Rodrigo M. P., Mietkiewska, Elzbieta, Pan, Xue, Weselake, Randall J.
The oil from flax (Linum usitatissimum L.) has high amounts of α-linolenic acid (ALA; 18:3cisΔ9,12,15) and is one of the richest sources of omega-3 polyunsaturated fatty acids (ω-3-PUFAs). To produce ∼57% ALA in triacylglycerol (TAG), it is likely that flax contains enzymes that can efficiently...