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Skip to Search Results- 46Exercise
- 18Alzheimer's disease
- 6Physical Activity
- 5Rehabilitation
- 4Cognitive impairment
- 4Physical activity
- 1Al Onazi, Mona Moraybed
- 1Benson, Curtis A
- 1Chenji, Sneha R.
- 1Clifford, Alexander M
- 1Cochrane, Karen
- 1Comeau, Aidan K
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Respiration, Acid/Base, Ammonia and Ionoregulatory Strategies in the Pacific hagfish (Eptatretus stoutii)
DownloadFall 2016
Hagfish feed on putrefied carrion, which poses several environmental challenges to the scavenger including hypoxia (Low PO2), hypercapnia (high PCO2) and high environmental ammonia (HEA). To any other organism, these conditions would be physiologically challenging; however, hagfish seem to have...
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Role of Glutamate and GABA in a mouse model expressing mutant human APP in the absence of NPC1 protein
DownloadSpring 2013
Cholesterol plays a critical role in Alzheimer’s disease (AD) pathogenesis, but the underlying mechanisms remain unclear. To address this issue we have generated a line of ANPC transgenic mice that overexpress mutant-human amyloid precursor protein in the absence of cholesterol transporting...
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Roles of the Insulin-like Growth Factor-II/Cation-independent Mannose 6-phosphate Receptor and Cathepsin D in Alzheimer’s Disease Pathology
DownloadSpring 2016
Alzheimer’s disease (AD) is the most common type of senile dementia affecting the elderly. A critical contributing factor to the neurodegeneration and development of AD pathology stems from the processing of amyloid precursor protein (APP), leading to the generation of β-amyloid (Aβ) peptides....
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Fall 2009
Skeletal muscle is a heterogeneous, multinucleated, post-mitotic tissue that contains many functionally diverse fibre types that are capable of adjusting their phenotypic properties in response to altered contractile demands. This plasticity, or adaptability of skeletal muscle is largely...
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Fall 2020
Tauopathies are a class of neurological disorders associated with the aggregation of the tau protein into neurofibrillary tangles. The most prominent tauopathy is Alzheimer’s disease (AD), which presents as two forms: early onset (familial, fAD) and late onset (sporadic, sAD). sAD does not have a...
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The effect of aerobic fitness on the cardiovascular and sympathetic nervous system response to physiological stress at rest and during dynamic exercise
DownloadFall 2012
A cardio-protective adaptation associated with aerobic fitness may be an attenuated sympathetic nervous system (SNS) and cardiovascular response to stress. The hypothesis that the cardiovascular and SNS responses to physiological stress at rest and during exercise would be a function of...
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Spring 2010
The effects of exercise intensity on post-exercise measures of intestinal permeability and absorption in sedentary and in active young men were examined in this study. Measures were compared bewteen rest, low intensity and high intensity interval exercise interventions. In spite of the exercise...
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The effects of physical activity messages tailored to social setting on extraverts' and introverts' exercise-related social cognitions
DownloadSpring 2015
This thesis explored the effects of tailoring exercise messages to social setting based on the personality domain of extraversion on participants’ exercise-related social cognitions. Messages were tailored to either exercising alone (introverted social context) or exercising with others...
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The Feasibility and Acceptability of a Virtually-Supported Home Exercise Program for People with Multiple Myeloma
DownloadFall 2021
Introduction: Exercise could help alleviate the significant morbidity experienced by people with multiple myeloma (MM). It is unclear if current cancer-specific exercise guidelines are appropriate for this unique population. Supervision, tailoring, and flexibility are proposed as key program...
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Spring 2022
Background: Carbon monoxide alters cardiovascular function through its actions as a signaling molecule and by limiting oxygen delivery in the blood, favouring pro-dilatory and anti-constrictor effects within the vasculature. The impacts of mild carbon monoxide exposure on vascular responses to...