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Skip to Search Results- 4Löbenberg, Raimar
- 3Azarmi, Shirzad
- 3Finlay, Warren H.
- 2Roa, Wilson
- 2Roa, Wilson H.
- 1Al-Hallak, M. H. D. Kamal
- 19Graduate and Postdoctoral Studies (GPS), Faculty of
- 19Graduate and Postdoctoral Studies (GPS), Faculty of/Theses and Dissertations
- 5Pharmacy and Pharmaceutical Sciences, Faculty of
- 5Pharmacy and Pharmaceutical Sciences, Faculty of/Journal Articles (Pharmacy and Pharmaceutical Sciences)
- 1Biological Sciences, Department of
- 1Biological Sciences, Department of/Journal Articles (Biological Sciences)
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Experimental and theoretical studies on the particle formation process of particles for the improvement of pulmonary drug delivery
DownloadFall 2016
The formation of dry microparticles from evaporating solution droplets was investigated and analyzed. The particle formation involved the creation and production of spray dried microparticles used for the delivery of drugs to treat pulmonary diseases. Studies of particle formation were conducted...
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Fall 2021
In this thesis, several fundamental studies were conducted to tackle some of the unanswered questions in the design and engineering of inhalable microparticles produced via spray drying. Different experimental and theoretical methods were applied to understand the mechanisms that control particle...
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Improving Measurements of the Mixing State and Mass Concentration of Particulate Emissions from Aircraft Engines
DownloadSpring 2016
This research is focused towards improving techniques used to measure particulate emissions from aircraft engines, on two fronts: first, to characterize and quantify the mixing state of particulate emissions; and second, to calibrate black carbon mass instruments with a traceable mass...
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Nanodelivery of Novel Inhibitors of ERCC1/XPF for sensitizing colorectal cancer cell to platinum drugs
DownloadSpring 2023
This project's long-term goal is to increase the efficacy of genotoxic therapeutics through thesensitization of cells to DNA-damaging therapy ahead of the treatment. The focus of this projectwas on the enhancement of platinum-based chemotherapeutics in colorectal cancer usingcolorectal cancer...
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Spring 2012
The present thesis describes preliminary studies required for evaluating silicon nanocrystals (Si-NCs) as photothermal (PT) therapy agents and drug delivery vehicles. Group 14 semiconductor NCs are of particular interest for these applications because of their tailorable optical response and...
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Poly n-butylcyanoacrylate (PNBCA) nanocapsules as a carrier for NSAIDs: in vitro release and in vivo skin penetration
Download2003
Kubo, W., Takahashi, A., Miyazaki, S., Löbenberg, R., Bachynsky, J.
Abstract: Purpose: The aim of this work was to prepare poly n-butylcyanoacrylate (PNBCA) nanocapsules loaded with indomethacin and to evaluate the ability of this carrier system to deliver the drug systemically after its topical application. Methods: Poly n-butylcyanoacrylate (PNBCA) nanocapsules...
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Spring 2018
The centrifugal particle mass analyzer (CPMA)-electrometer system has been proposed as an alternative method of calibration for devices that measure black carbon. This system is proposed to replace the current calibration standard of NIOSH 5040. The repeatability and intermediate precision of the...
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Fall 2020
Infectious respiratory diseases, caused by viruses and bacteria that attack the respiratory system, constitute a serious threat in public health around the world. Pathogens can be transmitted in the air though large droplets or aerosols. As aerosols can linger in the environment for a prolonged...