Search
Skip to Search Results- 1Dickau, Matthew A
- 1Golshahi, Laleh
- 1Graves, Brian M
- 1Lu, Lei
- 1Martinez, Roberto Carlos
- 1Mehinrad, Parnian
-
Fall 2023
Background: The COVID-19 pandemic has shown us that our infection prevention and control (IPC) knowledge has some glaring gaps on what best ways to treat dental patients, leading to a flurry of research to understand the best mitigation strategies to reduce aerosols. One of these strategies...
-
Spring 2011
The objective of this thesis is to design nanoparticle (NP)-based drug delivery systems suitable for treatment of bone diseases. Two types of nanocarriers, (1) polymer coated bovine serum albumin (BSA) NPs and (2) lipid based NPs (micelles and liposomes) were investigated. The BSA NPs were...
-
Cell-electronic Sensing of Cellular Responses and Toxicity Induced by Nanoparticles and Arsenic Species
DownloadFall 2013
We demonstrate the development of a real-time cell analysis (RTCA) platform for studying nanoparticle- and arsenic-induced cytotoxicity with potential applications to risk assessment, environmental toxicity monitoring, and drug development. RTCA is an impedance-based in vitro detection system...
-
Characterization of Particulate Matter Morphology and Volatility for Two Direct-Injection Engines
DownloadFall 2015
Particulate matter emitted from two direct injection engines has been characterized by morphology, volatility, mass-mobility exponent, effective density, and size distribution using tandem measurements from a centrifugal particle mass analyzer (CPMA) and differential mobility analyzers (DMA). The...
-
Development of Empirical Models to Predict Deposition of Aerosols in the Extrathoracic Airways of Children
DownloadSpring 2012
The experimental studies described in this thesis were performed with the goal of measuring deposition of aerosols, inhaled either nasally or orally, in the extrathoracic airways of children in different age groups. We pursued in vitro methods and characterized the deposition of aerosols in the...
-
Evaluation of Mask and Mask Material Suitability for COVID-19 Transmission Protection and Influence of Face Velocity and Exhaled Breath Condensate on Filtration Efficiency
DownloadSpring 2022
Facemask use has been a key public health measure in response to the SARS CoV-2 pandemic; they are used to reduce airborne transmission of the disease amongst the public. The facemasks used by the public are non-medical in nature and therefore are not regulated like medical masks. Cloth masks,...
-
Improving Measurements of the Mixing State and Mass Concentration of Particulate Emissions from Aircraft Engines
DownloadSpring 2016
This research is focused towards improving techniques used to measure particulate emissions from aircraft engines, on two fronts: first, to characterize and quantify the mixing state of particulate emissions; and second, to calibrate black carbon mass instruments with a traceable mass...
-
Nanodelivery of Novel Inhibitors of ERCC1/XPF for sensitizing colorectal cancer cell to platinum drugs
DownloadSpring 2023
This project's long-term goal is to increase the efficacy of genotoxic therapeutics through thesensitization of cells to DNA-damaging therapy ahead of the treatment. The focus of this projectwas on the enhancement of platinum-based chemotherapeutics in colorectal cancer usingcolorectal cancer...
-
Spring 2012
The present thesis describes preliminary studies required for evaluating silicon nanocrystals (Si-NCs) as photothermal (PT) therapy agents and drug delivery vehicles. Group 14 semiconductor NCs are of particular interest for these applications because of their tailorable optical response and...
-
Spring 2018
The centrifugal particle mass analyzer (CPMA)-electrometer system has been proposed as an alternative method of calibration for devices that measure black carbon. This system is proposed to replace the current calibration standard of NIOSH 5040. The repeatability and intermediate precision of the...