Search

Fall 2018

Perri, Melissa

Background Worldwide, body surface area [BSA] is used to calculate chemotherapy dose. The BSA formula was originally developed in 1916, derived from height and weight, with no consideration of other patient characteristics. Most chemotherapy agents have a narrow therapeutic index and are...

Fall 2011

Pant, Asha

This study determined how chemotherapy treatment for colorectal cancer alters hepatic fat metabolism. Livers were isolated from tumor-bearing animals after one and two cycles of chemotherapy consisting of irinotecan plus 5-fluorouracil. Fatty acid amounts and composition within triglycerides (TG)...

Fall 2018

Hopkins, Jessica Jean

Both tumor biology and host-specific factors play an important role in the prognosis of colorectal cancer. Body composition is an emerging patient-specific factor, which is currently being elucidated. Opportunistic analysis of pre-existing staging computed tomography scans can be used to quantify...

Spring 2024

Batycky, Anya

Hydrolyzed polyacrylamide (HPAM) is a common flocculant used in oil sands tailings dewatering technologies. Although HPAM is regularly used in tailings treatment and will eventually be incorporated into the reclaimed landscape of the oil sands, there are knowledge gaps surrounding the environment...

Fall 2020

Orsso, Camila Estefani

Adipose tissue and skeletal muscle have unique metabolic roles. Despite body mass index for age and sex (BMI z-score) being historically widely used to evaluate and monitor health status in children with obesity, it does not depict adiposity and muscularity (or their changes) during growth or...

Fall 2010

Crisp, Nicole

Escalating cancer rates and an increase in the complexity and duration of chemotherapy regimens have brought the issue of cancer treatment at home to the forefront. For the participants of this study, home chemotherapy was offered as a potential treatment choice. Ten patients who accepted were...

Spring 2015

Hewitt, Joanne D

Despite the research to date, the characteristics and impact of cognitive dysfunction (CD) in cancer patients following chemotherapy is still not well understood. It is estimated approximately 20% of patients will manifest measurable cognitive deficits on neuropsychological testing...

Fall 2015

Ayoub, Ahmed T

Microtubules are cellular structures that are crucial to many cellular functions including maintenance of cell shape, vesicular transport, and cell division. The dynamic instability of microtubules is the basic feature which enables them to do their cellular functions. Their pivotal role in cell...

Fall 2012

Shahin, Mostafa H

Conventional chemotherapy agents can kill tumor cells and inhibit tumor growth, but they produce severe side effects on normal cells at the same time. To shift the balance towards tumoral effects, it would be desirable to direct the anti-cancer drug towards tumor while restricting drug access to...

Spring 2017

Almasud,Alaa A

Background: Myosteatosis is defined as low skeletal muscle radio-density with elevated amounts of intermuscular adipose tissue, assessed using computed tomography. Myosteatosis has been recently observed to be associated with mortality in people with cancer. Previous work from our lab reported...