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Skip to Search Results- 8Department of Agricultural, Food, and Nutritional Science
- 3Department of Physiology
- 2Department of Biochemistry
- 2Department of Pharmacology
- 1Centre for Neuroscience
- 1Department of Agricultural, Food and Nutritional Science
- 2Proctor, Spencer (AFNS)
- 1Curtis, Jonathan (Agricultural, Food and Nutritional Science)
- 1Curtis, Jonathan (Department of Agricultural, Food and Nutritional Science)
- 1Davidge, Sandra T. (Physiology/Obstetrics and Gynecology)
- 1Dean Eurich (School of Public Health)
- 1Dr. David Bressler (Agricultural, Food and Nutritional Science)
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Spring 2010
Cost-effective processing of dairy whey permeates is important to the environment and economics of the agriculture industry in Canada. Bioconversion of whey permeates is an attractive means of obtaining value-added adjuncts with improved nutritional and functional properties. In the past,...
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Fall 2011
Coupling supercritical CO2 extraction with membrane separation leads to energy savings by recycling CO2 at supercritical state while separating extract components. Commercially available polyamide-based membranes are commonly used with coupled systems due to their availability and robust...
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Fall 2020
Interactions between diet, lifespan, metabolism, and immunity are complex but can have profound impact on human health. The Drosophila model is useful to study these interactions as many pathways and processes are highly conserved between flies and humans. In this thesis, I used the defined...
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Spring 2022
Background: In metabolic disease statues, such as diabetes and obesity, dyslipidemia is characterized by a dysregulation of lipid homeostasis, due in part to elevated triglyceride (TG)-rich very low-density lipoprotein (VLDL-TG) production and secretion by the liver. Further, these metabolic...
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In-line Ozonolysis coupled to Mass Spectrometry- A New Dimension of Structural Determination for Lipids
DownloadFall 2014
The location of double bonds within unsaturated lipids can greatly affect their biological functions. Liquid chromatography coupled to mass spectrometry (LC/MS) has become a powerful tool for lipid separation and structural elucidation. However, the determination of double bond position remains...
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J-Coupling Effects on Quantification of the 1.3 ppm Lipid Methylene Resonance with In-Vivo Magnetic Resonance Spectroscopy at 3 T
DownloadFall 2015
Quantification of 1.3 ppm lipid methylene protons by proton magnetic resonance spectroscopy has been shown to be relevant to a number of diseases. Additionally, T2 estimation of 1.3 ppm methylene protons has been used to grade the metastatic potential of colon tumours. J-coupling...
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Fall 2016
Lipidomics is a research field that attempts to achieve the comprehensive analysis of the entire lipidome in a biological system. The emergence and rapid expansion of lipidomic studies is driven by the great advances in chromatographic separation and mass spectrometry. For this dissertation, I...
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Spring 2013
Huntington disease (HD) is a neurodegenerative disorder characterized by motor and cognitive symptoms. In HD patients, the protein huntingtin contains an abnormal expansion of a polyglutamine tract, which leads to the selective dysfunction and death of striatal and cortical neurons. Among other...
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Spring 2015
Protein silencing by small interfering RNA (siRNA) is a promising treatment strategy for cancer as over-expression of proteins is largely responsible for cancer cells’ infinite proliferation, evasion of cell death and multi-drug resistance. However, siRNAs require a carrier as their biological...