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Skip to Search Results- 1Adams, Scott C
- 1Borthwick, Faye
- 1Bruce, Sharon
- 1Cardenas-Turanzas, Marylou
- 1Casey, D.M.
- 1Chakrabarti, Subhadeep
- 14Graduate and Postdoctoral Studies (GPS), Faculty of
- 14Graduate and Postdoctoral Studies (GPS), Faculty of /Theses and Dissertations
- 6Nursing, Faculty of
- 2Agricultural, Food and Nutritional Science, Department of
- 2Agricultural, Food and Nutritional Science, Department of/Journal Articles (Agricultural, Food and Nutritional Science)
- 2Nursing, Faculty of/Health Equity
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Analysis of risk factors for Tuberculosis Recurrence using a population-based TB/HIV integrated surveillance database in Chiang Rai, Thailand
DownloadSpring 2011
TB recurrence is defined as a new episode of bacteriologically positive TB in a patient previously declared “successfully completed treatment.” Our study objective was to identify risk factors of recurrence among HIV-infected and HIV-uninfected TB patients. Based on a population-based TB/HIV...
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Binding, internalization, and transgene expression of an adenoviral vector retargeted to HER3/4
DownloadFall 2013
Adenoviruses (Ads) have been well studied for use in cancer gene therapy. However, low levels of the primary receptor, coxsackie-adenovirus receptor (CAR), in tumor cells has been shown to be a factor in low transgene expression. To increase Ad infection of breast cancer cells we constructed a...
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Fall 2021
Wind energy is emerging as a primary source of renewable energy in Canada, attracting over $23 billion in investment. Steadily increasing, a total capacity of 31,640 MW of wind energy must be installed by 2040 to meet the requirements of the Paris Agreement on Climate, requiring the construction...
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Fall 2011
The prevalence of childhood obesity has increased dramatically over the last three decades in Canada with substantial consequences for the physical, mental, and economic wellbeing of the population. The overarching objective of this thesis was to examine the various aspects of childhood obesity...
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Development of a Targeted Adenoviral Vector Expressing HSV-TK for use in Breast Cancer Gene Therapy and Analysis through Positron Emission Tomography
DownloadFall 2012
While adenoviral (Ad) vectors are the most commonly used gene delivery vector for human gene therapy, improvements must be made to increase Ad specificity to tumors if they are to be used for cancer gene therapy. Our goal is to target adenoviral vectors to breast cancer (BrCa) cells to induce...
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Differential expression of hypothalamic metabolic and inflammatory genes in response to short-term calorie restriction in juvenile obese- and lean-prone JCR rats
Download2015
Vine, Donna F., Jacobs, Rene, Pierce, W.D., Heth, C.D., Russell, Jim, Proctor, Spencer D., Borthwick, Faye, Nelson, Randy, Diane, Abdoulaye, Mangat, Rabban
Background: Childhood obesity is an important early predictor of adult obesity and associated comorbidities. Common forms of obesity are underpinned by both environmental and genetic factors. However, the rising prevalence of obesity in genetically stable populations strongly suggests that...
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2012
Williams, R.J., Casey, D.M., el-Guebaly, N., Schopflocher, D. P., Currie, S.R., Smith, G.J., Martin, C. R., Hodgins, D. C.
Background When gambling opportunities are made available to the public in a given jurisdiction, some individuals participate occasionally and others more frequently. Among frequent gamblers, some individuals develop problematic involvement and some do not. This study addresses the association...
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Effect of Adenovirus-mediated Decorin Gene Therapy on Fibrotic Remodeling in Tissue-engineered Skin
DownloadFall 2016
Background: Hypertrophic scar (HTS) is a fibroproliferative disorder of the skin that results in the development of painful, red, raised scar lesions. Transforming growth factor beta 1 (TGF-β1) has been implicated as a key driver of this disorder. Primarily, these effects include an increased...
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Effect of obesity on short- and long-term mortality postcoronary revascularization: a meta-analysis.
Download2008
Kalantar-Zadeh, K., Mullen, J.C., Pretorius, V., Padwal, R., Oreopoulos, A., Norris, C.M.
Objective: Overweight and obesity are often assumed to be risk factors for postprocedural mortality in patients with coronary artery disease (CAD). However, recent studies have described an “obesity paradox”—a neutral or beneficial association between obesity and mortality postcoronary...