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Skip to Search Results- 8Fish
- 5Comparative immunology
- 4Immunoregulatory receptors
- 3Innate immunity
- 3Phagocytosis
- 2Intracellular signaling
- 1Blunt, Brian
- 1Blyth, Graham AD
- 1Cortes, Herman D
- 1Fei,Chenjie
- 1Felix, Lindsey C
- 1Folkerts, Erik John
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Fall 2009
I investigated cellular mechanisms of ion and acid-base transport in rainbow trout (Oncorhyncus mykiss), crabs (Neohelice granulata), zebrafish (Danio rerio), Pacific hagfish (Eptatretus stoutii), and mosquito larvae (Aedes aegypti) with a primary focus on discerning the mechanisms governing ion...
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Spring 2012
Decades of fish introductions into mountain lakes have altered invertebrate communities. I assessed the current status of fish populations and their effects on crustacean zooplankton communities by sampling 37 lakes in the mountain parks, where stocking practices had been halted over 25 years...
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Examination of channel catfish (Ictalurus punctatus) leukocyte immune-type receptor-mediated crosstalk regulation of phagocytosis
DownloadFall 2020
Across vertebrates, innate immune cells are capable of initiating a range of potent effector responses that are designed to destroy or contain foreign microbial invaders. The execution and regulation of various innate cellular responses is mediated by a dedicated repertoire of cell...
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Fall 2013
In response to pathogens, immune cells induce protective effector functions, such as degranulation, phagocytosis and cytokine secretion, which are initiated by stimulatory or inhibitory immunoregulatory receptors expressed on leukocytes. Using a fish immunological model system, the focus of my...
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Spring 2014
Anthropogenic contaminants can impair olfactory responses to natural odorants. In fishes, these impairments may be used as a metric of sub-lethal toxicity. My studies aimed to determine the effects of two contaminant sources on fish olfaction as measured by electro-olfactography (EOG). The...
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Spring 2015
Interferon Inducible Transmembrane Proteins (IFITMs) can restrict the entry of a wide range of viruses. IFITM3 localizes to endosomes and can potently restrict the replication the influenza A virus (IAV), and several other viruses that also enter host cells through the endocytic pathway. Given...
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Identification and Molecular Characterization of Zebrafish (Danio rerio) Leukocyte Immune-Type Receptors (DrLITRs)
DownloadSpring 2020
In response to foreign invaders, innate immune cells use cell surface-expressed receptors to trigger intracellular signalling cascades that control various effector responses designed to destroy microbes. These specialized receptors are known as immunoregulatory receptors and structurally they...
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Fall 2017
Since antiquity, fever has been documented as a physiological response to infection characterized by an increase in body temperature. Though fever is commonly regarded as a deleterious symptom of inflammation and is often suppressed using NSAID drugs, little is known about the effects that fever...
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The biology and characterization of NOD-like receptors in goldfish (Carassius auratus L.) macrophages exposed to bacterial pathogens
DownloadSpring 2017
The recognition of pathogen-associated molecular patterns (PAMPs) by pattern recognition receptors (PRRs) is important for the initiation of the host defense against pathogens. NOD-like receptors (NLRs) are a family of PRRs that primarily detect the cytosolic PAMPs of the pathogens. The NLRs have...
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Toxicological Characterization of Hydraulic Fracturing Flowback and Produced Water Exposures to Aquatic Organisms
DownloadFall 2021
Hydraulic fracturing is an unconventional oil and gas extraction method used to liberate oil and gas reserves from low permeability geological formations by injecting large quantities of fracturing fluid into the well-bore under high pressures. A by-product of this process is flowback and...