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A Retrospective Analysis of the Safety and Efficacy of a 6-Week Pulmonary Rehabilitation Program in Patients with Severe Pulmonary Arterial Hypertension
DownloadSpring 2014
Pulmonary Arterial Hypertension (PAH) is progressive disease characterized by reduced exercise capacity and decreased quality of life. Despite the availability of disease targeted therapies outcomes remain sub-optimal. Pulmonary Rehabilitation has proven to improve outcomes in other chronic...
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Investigating the Effects of N2-Acetylphenelzine in the Sexes in Experimental Autoimmune Encephalomyelitis
DownloadFall 2017
Chronic pain is a highly prevalent symptom in Multiple Sclerosis (MS) and affects approximately half of patients at some stage of the disease. MS affects women more frequently than men and neuropathic pain is also reported as more severe, and frequent, in females with the disease. The underlying...
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The effect of eight weeks of home based aerobic exercise training on peak exercise oxygen consumption, six-minute walk test distance, thigh muscle mass, and health related quality of life in Child Pugh class A and B cirrhosis patients
DownloadFall 2017
Purpose: Cirrhosis patients have reduced peak aerobic power (peak VO2) that is associated with reduced survival. Supervised endurance training is an effective therapy to increase exercise tolerance in cirrhosis. The effect of home-based endurance exercise training (HET) on improving peak VO2 in...
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Βeta-adrenergic receptors and opposition of evoked sympathetic vasoconstriction: Effects of sex and exercise training
DownloadFall 2016
Stimulation of the sympathetic nervous system evokes the release of neurotransmitters and produces vasoconstriction that is primarily mediated by the binding of norepinephrine (NE) to alpha-adrenergic receptors. However, NE may also bind to beta (β)-adrenergic receptors and produce vasodilation...