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Formulating food protein-stabilized indomethacin nanosuspensions into pellets by fluid-bed coating technology: Physical characterization, redispersibility, and dissolution
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Yin, Lifang, Wu, Wei, He, Wei, Chen, Lingyun, Lu, Yi, Qi, Jianping
Background: Drug nanosuspensions are very promising for enhancing the dissolution and bioavailability of drugs that are poorly soluble in water. However, the poor stability of nanosuspensions, reflected in particle growth, aggregation/agglomeration, and change in crystallinity state greatly...
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