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Skip to Search Results- 20Chan, Catherine B.
- 12Bell, Rhonda C.
- 7Wheeler, Michael B.
- 4Koshkin, Vasilij
- 3Field, Catherine J.
- 3McCargar, Linda J.
- 6Bioenergetics
- 6Metabolism
- 3Diabetes
- 3Physical Activity
- 2Adipose Tissue
- 2Advanced Glycation End Products
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Isoferulic acid, a new anti-glycation agent, inhibits fructose- and glucose-mediated protein glycation in vitro
Download2013
Meeprom, Aramsri, Adisakwattana, Sirichai, Sompong, Weerachat, Chan, Catherine B.
The inhibitory activity of isoferulic acid (IFA) on fructose- and glucose-mediated protein glycation and oxidation of bovine serum albumin (BSA) was investigated. Our data showed that IFA (1.25–5 mM) inhibited the formation of fluorescent advanced glycation end products (AGEs) and non-fluorescent...
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Limited mitochondrial permeabilization is an early manifestation of palmitate-induced lipotoxicity in pancreatic ß-cells
Download2008
Wheeler, Michael B., Chan, Catherine B., Dai, Feihan F., Koshkin, Vasilij, Robson-Doucette, Christine A.
Involvement of the mitochondrial permeability transition (MPT) pore in early stages of lipotoxic stress in the pancreatic β-cell lines MIN6 and INS-1 was the focus of this study. Both long term (indirect) and acute (direct) effects of fatty acid (FA) application on β-cell susceptibility to...
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2003
Chan, Catherine B., Wang, Xiaolin, Koshkin, Vasilij, Wheeler, Michael B., Scherer, Philipp E.
Excessive free fatty acid (FFA) exposure represents a potentially important diabetogenic condition that can impair insulin secretion from pancreatic β-cells. Because mitochondrial oxidative phosphorylation is a main link between glucose metabolism and insulin secretion, in the present work we...
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Predictors of exclusive breastfeeding: Observations from the Alberta pregnancy outcomes and nutrition (APrON) study
Download2013
Bell, Rhonda C., Maximova, Katerina, Jessri, Mahsa, Farmer, Anna, Willows, Noreen
Background Despite growing evidence that supports the importance of 6-month exclusive breastfeeding, few Canadian mothers adhere to this, and early weaning onto solids is a common practice. This study assessed infant feeding transitions during the first 6 months postpartum and factors that...
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Relationship between objective measures of physical activity and weather: A longitudinal study
Download2006
Ryan, Daniel A. J., Chan, Catherine B., Tudor-Locke, Catrine
Background The weather may be a barrier to physical activity but objective assessment of this hypothesis is lacking. Therefore we evaluated the effect of temperature, rain or snow, and wind speed on the daily physical activity of adults. Methods This report contains data from 25 males (BMI (mean...
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The characterization of mitochondrial permeability transition (MPT) in clonal pancreatic beta cells: Multiple modes and regulation
Download2004
Chan, Catherine B., Bikopoulos, George, Koshkin, Vasilij, Wheeler, Michael B.
Mitochondrial permeability transition (MPT), which contributes substantially to the regulation of normal mitochondrial metabolism, also plays a crucial role in the initiation of cell death. It is known that MPT is regulated in a tissue-specific manner. The importance of MPT in the pancreatic...
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The reliability and validity of the perceived dietary adherence questionnaire for people with type 2 diabetes
Download2015
Soria-Contreras, Diana C., Xu, Yunke, Asaad, Ghada, Sadegian, Maryam, Lau, Rita, Chan, Catherine B., Bell, Rhonda C.
Nutrition therapy is essential for diabetes treatment, and assessment of dietary intake can be time consuming. The purpose of this study was to develop a reliable and valid instrument to measure diabetic patients’ adherence to Canadian diabetes nutrition recommendations. Specific information...
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2014
Jenkins, David, Mechanick, Jeffrey I., Marchetti, Albert, Sievenpiper, John L., Camelon, Kathryn, Hegazi, Refaat A., Dupre, John, Despres, Jean-Pierre, Hamdy, Osama, Ransom, Thomas P. P., Yale, Jean-François, Bell, Rhonda C., Kendall, Cyril, Gougeon, Réjeanne E.
The Transcultural Diabetes Nutrition Algorithm (tDNA) is a clinical tool designed to facilitate implementation of therapeutic lifestyle recommendations for people with or at risk for type 2 diabetes. Cultural adaptation of evidence-based clinical practice guidelines (CPG) recommendations is...
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Transcriptional regulation of lipid metabolism: A key determinant of pancreatic ß-cell function
Download2005
Fatehi-Hassanabad, Zahra, Chan, Catherine B.
Background Optimal pancreatic β-cell function is essential for the regulation of glucose homeostasis in both humans and animals and its impairment leads to the development of diabetes. Type 2 diabetes is a polygenic disease aggravated by environmental factors such as low physical activity or a...