A Quantitative Analysis of Four Dimensional Computed Tomography

  • Author / Creator
    Noice, Lori
  • This project assesses the four dimensional computed tomography (4DCT) capabilities of the Philips Brilliance Big Bore CT scanner (Philips Medical Systems, Cleveland, OH). A mechanical phantom imparts clinically relevant motions to acrylic spheres of various diameters. The size, shape, and position of these spheres, as measured with 4DCT, are compared to their true size, shape, and position. An evaluation of image quality is also performed. Maximum discrepancies between physical and imaged volumes, for all sphere sizes and motion ranges, did not exceed 2.6 mm (mean = 1.2 mm, standard deviation = 0.4 mm). For approximately tissue equivalent density objects, mean CT# in 4DCT images differed from those in standard clinical thoracic images by only a few Hounsfield units. Measured geometric precision along with the accuracy of mean CT#s observed in 4DCT phase images indicate that 4DCT is an appropriate imaging technique for treatment planning.

  • Subjects / Keywords
  • Graduation date
  • Type of Item
  • Degree
    Master of Science
  • DOI
  • License
    This thesis is made available by the University of Alberta Libraries with permission of the copyright owner solely for non-commercial purposes. This thesis, or any portion thereof, may not otherwise be copied or reproduced without the written consent of the copyright owner, except to the extent permitted by Canadian copyright law.
  • Language
  • Institution
    University of Alberta
  • Degree level
  • Department
    • Physics
  • Supervisor / co-supervisor and their department(s)
    • Dr. Don Robinson
  • Examining committee members and their departments
    • Dr. Ron Sloboda
    • Dr. Sharon Morsink
    • Dr. Terence Riauka