Preliminary Analysis of Dietary Sugar Consumption During Pregnancy Using a Potential Biomarker of Urinary Fructose Excretion

• Author / Creator

  Dahlawi, Doaa H

• A 24 hour urinary fructose excretion correlates with total sugar intakes. However, whether or not a random (“spot”) urinary fructose measurement is a reliable biomarker of fructose intake is not known. This study was done to determine the extent to which it is possible to estimate fructose intake in women using a biomarker of urinary fructose. Pregnant women were recruited from the Sweet Moms project (n=135) and provided a spot urine sample. Urinary fructose was enzymatically measured using a kit for measuring glucose and fructose. No correlation between fructose concentrations in urine sample and the fructose consumption in pregnant women. A validation study was performed on non pregnant women (n=9) after four hours to examine the validity of a urinary biomarker. Fructose excretion by non-pregnant women was positively associated with fructose ingestion. Fructose intake in pregnant women continues to be difficult to measure with currently available biomarkers.

• Subjects / Keywords

  • Fructose
  • Pregnancy
  • Urinary biomarker

• Graduation date

  Spring 2014

• Type of Item

  Thesis

• Degree

  Master of Science

• DOI

  https://doi.org/10.7939/R3DR2PG4D

• License

  This thesis is made available by the University of Alberta Libraries with permission of the copyright owner solely for non-commercial purposes. This thesis, or any portion thereof, may not otherwise be copied or reproduced without the written consent of the copyright owner, except to the extent permitted by Canadian copyright law.