Journal Articles (Kinsella Ranch)
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A 2cM resolution genome-wide scan of European Holstein cattle affected by classical BSE
Background Classical bovine spongiform encephalopathy (BSE) is an acquired prion disease that is invariably fatal in cattle and has been implicated as a significant human health risk. Polymorphisms that alter the prion protein of sheep or humans have been associated with variations in...
Gene duplications are common in the vertebrate genome, and duplicated loci often show a variation in copy number that may have important phenotypic effects. Here we describe a powerful method for quantification of duplicated copies based on pyrosequencing. A reliable quantification was obtained...
A Simple Polymerase Chain Reaction-based Method for the Discrimination of Three Chicken BreedsDownload
A large number of branded chicken products exist in Japan, and in some cases, the breed of chicken is an important factor used to attract consumer interest in the retail product. In order to establish a simple method for verifying such breed claims we applied the amplified fragment length...
A Whole-Genome Scan to Map Quantitative Trait Loci for Conformation and Functional Traits in Canadian Holstein BullsDownload
Genetic improvement of livestock populations can be achieved through detection and mapping of genetic markers linked to quantitative trait loci (QTL). With the completion of the bovine genome sequence assembly, single nucleotide polymorphism (SNP) assays spanning the whole bovine genome and...
A comparison of reproductive and growth traits of horned and polled cattle in three synthetic beef lines
A comparison of reproductive and growth traits of horned and polled cattle in three synthetic beef linesDownload
One hundred and thirty-seven cow-calf pairs on pasture in southeastern Alberta, were randomly allocated to one of two treatments no supplement (NOS) or a high by-pass protein (70% of CP) creep supplement (HPS) at an intake of 1.5 kg head−1 d−1. Calf weaning weights and pre-weaning ADG were higher...
A genome-wide association study of fetal response to type 2 porcine reproductive and respiratory syndrome virus challengeDownload
Control of porcine reproductive and respiratory syndrome (PRRS) is economically important for the swine industry worldwide. As current PRRS vaccines do not completely protect against heterologous challenge, alternative means of control, including enhanced genetic resilience, are needed. For...
A high resolution radiation hybrid map of bovine chromosome 14 identifies scaffold rearrangement in the latest bovine assembly
A high resolution radiation hybrid map of bovine chromosome 14 identifies scaffold rearrangement in the latest bovine assemblyDownload
Background Radiation hybrid (RH) maps are considered to be a tool of choice for fine mapping closely linked loci, considering that the resolution of linkage maps is determined by the number of informative meiosis and recombination events which may require very large mapping populations....
Arantes, Adriano S., Coros, Colin, Moore, Stephen, Liao, Xiaoping, Crowley, John J., Sargolzaei, Mehdi, Miller, Stephen P., Schenkel, Flavio, Stothard, Paul, Basarab, John A., De Pauw, Mary, Plastow, Graham S.
Background The Canadian Cattle Genome Project is a large-scale international project that aims to develop genomics-based tools to enhance the efficiency and sustainability of beef and dairy production. Obtaining DNA sequence information is an important part of achieving this goal as it...
A study of growth and carcass traits in dehorned and polled composite bulls
Phenotypically dehorned (genetically horned) and polled bulls were similar for birth, weaning weight, pre- and post-weaning ADG, carcass weight, grade fat, marbling, rib-eye area, cutability and carcass grade. Polled bulls had higher (P < 0.02) fat over the rib-eye compared with dehorned. The...
A technique for measuring linear bone growth during short time intervals in cattle
A technique is described for meausuring increases in bone length during defined periods before slaughter in cattle. It consists of jugular infusions of oxytetracycline at specified time intervals. Oxytetracycline identifies the sites of ossification in growing bones at the time of infusion by...