Synthesis of Substituted Resorcinol Monomethyl Ethers from 2-Bromo-3-methoxycyclohex-2-en-1-ones

• Author(s) / Creator(s)

  • Shao, Wenjie
  • Clive, Derrick L. J.

• 2-Bromo-3-methoxycyclohex-2-en-1-ones are readily alkylated at C-6 with
  reactive halides, and then treatment with DBU (2 equiv) in PhMe at room temperature results in
  smooth loss of bromide and aromatization to resorcinol (monomethyl ethers of defined
  substitution pattern.

• Date created

  2015-01-01

• Subjects / Keywords

  • Practical Synthesis
  • Coleophomone-B
  • Inhibitors
  • Olivetol
  • Analogs
  • Acid

• Type of Item

  Article (Draft / Submitted)

• DOI

  https://doi.org/10.7939/r3-75q0-sk96

• License

  This document is the Accepted Manuscript version of a Published Work that appeared in final form in Journal of Organic Chemistry, copyright © 2015 American Chemical Society after peer review and technical editing by the publisher. To access the final edited and published work see https://doi.org/10.1021/acs.joc.5b02187.