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Genome-wide Gametic and Zygotic Linkage Disequilibrium in a Composite Beef Population

  • Author / Creator
    Jiang, Qi
  • During 1960 to 1989, the University of Alberta Kinsella Research Ranch had established synthetic beef breeds as a cost-effective crossbreeding system. Animals from these synthetics were subsequently pooled to form a composite population. Despite many breeding and genomic studies on this population, little is known about its genetic structure. This thesis provided the first genome-wide survey of linkage disequilibrium (LD) at both gametic and zygotic levels for the Kinsella population. The survey was based on the genomic data consisting of 1,023 animals genotyped for 50K SNP markers. Similar genomic structures in gametic and zygotic LD were observed, with zygotic LD decaying faster than gametic LD over marker distance. The high-order trigenic and quadrigenic disequilibria were insignificant and decayed rapidly within a very short marker distance. These results support the current intensive focus on use of high-density markers for fine-scale mapping and genomic selection in the Kinsella population.

  • Subjects / Keywords
  • Graduation date
    2012-06
  • Type of Item
    Thesis
  • Degree
    Master of Science
  • DOI
    https://doi.org/10.7939/R3D03Q
  • License
    This thesis is made available by the University of Alberta Libraries with permission of the copyright owner solely for non-commercial purposes. This thesis, or any portion thereof, may not otherwise be copied or reproduced without the written consent of the copyright owner, except to the extent permitted by Canadian copyright law.
  • Language
    English
  • Institution
    University of Alberta
  • Degree level
    Master's
  • Department
    • Department of Agricultural, Food, and Nutritional Science
  • Specialization
    • Animal Science
  • Supervisor / co-supervisor and their department(s)
    • Yang, Rong-Cai (Agricultural, Food, and Nutritional Science)
    • Wang, Zhiquan (Agricultural, Food, and Nutritional Science)
  • Examining committee members and their departments
    • Dixon, Walter (Agricultural, Food, and Nutritional Science)
    • Plastow, Graham (Agricultural, Food, and Nutritional Science)
    • Zhang, Peng (Department of Mathematical and Statistical Sciences)
    • Wang, Zhiquan (Agricultural, Food, and Nutritional Science)
    • Yang, Rong-Cai (Agricultural, Food, and Nutritional Science)