One century later: Dissecting genetic effects for looking over old paradigms

• Author(s) / Creator(s)

  • Yang, Rong-Cai
  • Álvarez-Castro, José M.

• Introduction: The foundation of genetics as a scientific field at the beginning of the twentieth century was not free from controversy. It meant no resolution that the advocates of the Biometric and the Mendelian schools agreed in one thing: the inheritance laws Mendel inferred by studying meristic (discrete) traits did not seem to be compatible with the findings the biometricians had been reporting for continuous (quantitative) variation since the nineteenth century (see Provine, 1971). For providing conclusive evidence against that paradigm, Fisher (1918) developed the foundations of the mathematical models of genetic effects that remain pertinent today, an endeavor in which he developed statistical tools that soon became broadly used beyond genetics.

• Date created

  2014

• Subjects / Keywords

  • Mathematical Modeling
  • Genetic Effects
  • Statistical Estimation
  • Environmental Effects
  • Genetic Architecture

• Type of Item

  Article (Published)

• DOI

  https://doi.org/10.7939/R3BC3T98Q

• License

  Attribution 4.0 International