Associations between self-reported weight history and sarcopenic obesity in adults with knee osteoarthritis

• Author(s) / Creator(s)

  • Godziuk, Kristine
  • Prado, Carla M.
  • Woodhouse, Linda J.
  • Forhan, Mary

• Objective: Examine associations between self-reported weight history and sarcopenic obesity in adults with advanced knee osteoarthritis (OA).
  Methods: Self-reported weight history was collected from n=151 adults (58.9% female) with knee OA and a body mass index (BMI) ≥30 kg/m2 in a cross-sectional study. Body composition was assessed using dual-energy x-ray absorptiometry. Sarcopenic obesity was defined as appendicular skeletal muscle mass (ASM), adjusted by BMI, <0.51 kg/m2 in females and <0.79 kg/m2 in males; prevalence was 27.2%. Weight gain in the preceding year, weight gain ≥5% of body weight in past decade, and multiple weight cycling events in lifespan [loss of ≥10 lbs (4.5 kg) with regain ≥3 times] were examined using logistic regression (adjusted by age, sex and %fat mass), with the dependent variable of sarcopenic obesity presence.
  Results: Weight gain in the preceding year was associated with sarcopenic obesity (OR 2.45, 95%CI 1.02-5.87). No associations were found with weight gain in past decade (OR 1.04, 95%CI 0.43-2.5), or weight cycling (OR 0.86, 95%CI 0.37-2.01).
  Conclusions: In adults with obesity and advanced knee OA, self-reported weight gain in the preceding year was associated with sarcopenic obesity. This patient population may benefit from recommendations that prioritize prevention of weight gain.

• Date created

  2021-01-24

• Subjects / Keywords

  • Weight history
  • weight cycling
  • sarcopenia
  • obesity
  • osteoarthritis

• Type of Item

  Article (Published)

• DOI

  https://doi.org/10.7939/r3-g7hp-7y55

• License

  "This is the peer reviewed version of the following article: [Godziuk K, Prado CM, Woodhouse LJ, Forhan M. (2021). Associations Between Self-Reported Weight History and Sarcopenic Obesity in Adults with Knee Osteoarthritis. Obesity (Silver Spring). doi: 10.1002/oby.23074.], which has been published in final form at [https://doi.org/10.1002/oby.23074]. This article may be used for non-commercial purposes in accordance with Wiley Terms and Conditions for Use of Self-Archived Versions. This article may not be enhanced, enriched or otherwise transformed into a derivative work, without express permission from Wiley or by statutory rights under applicable legislation. Copyright notices must not be removed, obscured or modified. The article must be linked to Wiley’s version of record on Wiley Online Library and any embedding, framing or otherwise making available the article or pages thereof by third parties from platforms, services and websites other than Wiley Online Library must be prohibited."