Download the full-sized PDF of Effects of High Intensity Interval Exercise versus Moderate Intensity Continuous Exercise on Blood Glucose Profiles of Individuals with Type 2 DiabetesDownload the full-sized PDF



Permanent link (DOI):


Export to: EndNote  |  Zotero  |  Mendeley


This file is in the following communities:

Graduate Studies and Research, Faculty of


This file is in the following collections:

Theses and Dissertations

Effects of High Intensity Interval Exercise versus Moderate Intensity Continuous Exercise on Blood Glucose Profiles of Individuals with Type 2 Diabetes Open Access


Other title
glycemia, HIT, HIIE,
Type of item
Degree grantor
University of Alberta
Author or creator
Terada, Tasuku
Supervisor and department
Boulé, Normand (Physical Education and Recreation)
Examining committee member and department
Little, Jonathan (Health and Social Development)
McCargar, Linda (Agricultural Food and Nutritional Science)
Bell, Gordon (Physical Education and Recreation)
Chan, Catherine (Agricultural Food and Nutritional Science)
Physical Education and Recreation

Date accepted
Graduation date
Doctor of Philosophy
Degree level
Achieving good control over glucose concentrations is the fundamental therapeutic goal for individuals with type 2 diabetes (T2D). The effects of exercise on individuals with T2D have been well received and contributed extensively to recent evidence-based exercise guidelines in several countries. However, knowledge regarding the therapeutic benefits of high intensity interval exercise (HIIE) in individuals with T2D was limited. While accumulating evidence suggested the potential benefits of HIIE, it was unknown if it confers additional benefits over traditionally recommended moderate intensity continuous exercise (MICE) in improving the glycemia of T2D. In addition, it was unknown if timing to perform such exercise impacts glycemic responses. Accordingly, a series of studies were performed to: 1) examine the feasibility and long-term efficacy of HIIE; 2) to compare the glycemic responses to HIIE and MICE during exercise; and 3) to compare the acute glycemic responses to HIIE and MICE. Results suggested that HIIE is as feasible as MICE, and, compared to MICE, lowers glucose concentrations to a greater extent during exercise, and induces greater reductions in nocturnal and fasting glucose concentrations on the day subsequent to exercise. While performing HIIE in the fasted-state attenuated the reduction of glucose concentration during exercise, it improved most aspects of dysglycemia measured over hours following the exercise bouts. Postprandial HIIE, on the other hand, resulted in the greatest reduction in glycemia during exercise; however, no glucose profiles were improved hours after exercise as compared to a sedentary day. These results suggest that HIIE has some potential advantage over MICE in improving specific aspects of glycemia, and performing HIIE during a fasted-state may be more beneficial in lowering additional measures of glycemic profiles. In conclusions, HIIE is well tolerated by individuals with relatively well-controlled T2D and effectively improves various aspects of glycemia. The effects of HIIE may be magnified by performing it under fasted-state.
Permission is hereby granted to the University of Alberta Libraries to reproduce single copies of this thesis and to lend or sell such copies for private, scholarly or scientific research purposes only. Where the thesis is converted to, or otherwise made available in digital form, the University of Alberta will advise potential users of the thesis of these terms. The author reserves all other publication and other rights in association with the copyright in the thesis and, except as herein before provided, neither the thesis nor any substantial portion thereof may be printed or otherwise reproduced in any material form whatsoever without the author's prior written permission.
Citation for previous publication
Terada T, Loehr S, Guigard E, McCargar L, Bell G, Senior P, Boulé N. Test-retest reliability of a continuous glucose monitoring system in individuals with type 2 diabetes. Diabetes Technology & Therapeutics 2014 May [Epub ahead of print].Terada T, Friesen A, Chahal B, Bell G, McCargar L, Boulé N. Feasibility and preliminary efficacy of high intensity interval training in type 2 diabetes. Diabetes Research & Clinical Practice. 2013,99(2):120-129.Terada T, Friesen A, Chahal B, Bell G, McCargar L, Boulé N. Exploring the variability in acute glycemic responses to interval and continuous exercise training in type 2 diabetes. Journal of Diabetes Research, vol. 2013, Article ID 591574. Doi:10.1155/2013/591573.

File Details

Date Uploaded
Date Modified
Audit Status
Audits have not yet been run on this file.
File format: pdf (PDF/A)
Mime type: application/pdf
File size: 3617263
Last modified: 2015:10:12 12:44:35-06:00
Filename: Terada_Tasuku_201408_PhD.pdf
Original checksum: e45e445fddc10e9f252cd8efce2fb45a
Activity of users you follow
User Activity Date