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Permanent link (DOI): https://doi.org/10.7939/R37W81

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Longitudinal performance of Neuropsychological Assessments in Parkinson’s Disease. Open Access

Descriptions

Other title
Subject/Keyword
Mini-Mental State Exam
Cognitive impairment
Parkinson's Disease
Dementia Rating Scale
Clock Drawing test
Frontal Assessment Battery
Type of item
Thesis
Degree grantor
University of Alberta
Author or creator
Muayqil, Taim
Supervisor and department
Senthilselvan, Ambikaipakan (Public Health Sciences)
Camicioli, Richard (Medicine)
Examining committee member and department
Senthilselvan, Ambikaipakan (Public Health Sciences)
Camicioli, Richard (Medicine)
Kalra, Sanjay (Medicine)
Jeerakathil, Thomas (Medicine)
Department
School of Public Health Sciences
Specialization
Clinical Epidemiology
Date accepted
2012-09-24T14:14:00Z
Graduation date
2012-09
Degree
Master of Science
Degree level
Master's
Abstract
Parkinson’s disease (PD) involves the motor system and can lead to dementia. Dementia incidence among 102 non-demented participants (52 PD and 50 controls) followed prospectively over three years was assessed. Cognition was measured annually using the Clock Drawing Test (CDT), Mini-Mental State Exam (MMSE), Frontal Assessment Battery (FAB) and Dementia Rating Scale (DRS). Mixed-effects model was used to determine the significance of the change in neuropsychological tests (NPT) over time. Incidence of dementia in the PD group was 41.67%. The FAB and DRS showed significant. In the PD subgroup, the copy-CDT (CCDT), FAB and DRS showed decline in patients with incipient dementia (PDID). The FAB and DRS scores correlated in the primary and subgroup analyses. In the subgroup, the CCDT correlated with FAB and DRS. The NPT were useful in discriminating PD from control patients with early cognitive impairments and discriminating PDID from PDND.
Language
English
DOI
doi:10.7939/R37W81
Rights
Permission is hereby granted to the University of Alberta Libraries to reproduce single copies of this thesis and to lend or sell such copies for private, scholarly or scientific research purposes only. Where the thesis is converted to, or otherwise made available in digital form, the University of Alberta will advise potential users of the thesis of these terms. The author reserves all other publication and other rights in association with the copyright in the thesis and, except as herein before provided, neither the thesis nor any substantial portion thereof may be printed or otherwise reproduced in any material form whatsoever without the author's prior written permission.
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File format: pdf (Portable Document Format)
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File size: 2004542
Last modified: 2015:10:12 11:54:58-06:00
Filename: Muayqil_Taim_Fall 2012.pdf
Original checksum: b327c0a5ec57248383fb616b1284e9d7
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File title: Microsoft Word - Final-CDPD 17sep12.doc
File author: Taim Muayqil
Page count: 96
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