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- 5Parkinson's Disease
- 1Clinical Information Analysis
- 1Clock Drawing test
- 1Cognitive impairment
- 1Dementia Rating Scale
Voice Choral Singing Therapy has been gaining interest as an alternative form of voice therapy for persons with Parkinson’s disease. Often Voice Choral Singing Therapy employs individual and/or group singing activities to improve phonation. The present thesis follows this trend. A professional...
α-Synuclein has been implicated in the progression of Parkinson’s disease, a neurodegenerative disorder that affects millions of people worldwide. This work reports on the structural propensity and druggability of this protein using a combination of Monte Carlo, Molecular Dynamics, and Virtual...
Intelligent Parkinson's Disease Classification and Progress Monitoring using Non-invasive TechniquesDownload
Parkinson's disease (PD) is the second major neuro-degenerative disorder caused by dopaminergic loss in the brain region known as the Substantia Nigra (SN). The major symptoms of this disease are motor and non-motor abnormalities, which may show at early stages of PD. Physical exam, demographic...
Parkinson’s disease (PD) involves the motor system and can lead to dementia. Dementia incidence among 102 non-demented participants (52 PD and 50 controls) followed prospectively over three years was assessed. Cognition was measured annually using the Clock Drawing Test (CDT), Mini-Mental State...
PINK1 (Phosphatase Tensin homologue (PTEN)-Induced Kinase) is a neuroprotective kinase involved in mitochondrial dynamics. It is composed of an N-terminal mitochondrial targeting sequence, transmembrane domain and C-terminal kinase domain. PINK1 is imported into mitochondria and anchored into the...