Download the full-sized PDF of Sex Differences in the Relationship between Childhood Trauma and Cardiovascular Disease Risk in AdulthoodDownload the full-sized PDF



Permanent link (DOI):


Export to: EndNote  |  Zotero  |  Mendeley


This file is in the following communities:

Graduate Studies and Research, Faculty of


This file is in the following collections:

Theses and Dissertations

Sex Differences in the Relationship between Childhood Trauma and Cardiovascular Disease Risk in Adulthood Open Access


Other title
Cardiovascular Disease
Allostatic Load
Childhood Trauma
Lifecourse epidemiology
Type of item
Degree grantor
University of Alberta
Author or creator
Garad, Hayat
Supervisor and department
Colman, Ian (Epidemiology and Community Medicine)
Maximova, Katerina (School of Public Health Sciences)
Examining committee member and department
Nykiforuk, Candace (School of Public Health Sciences)
Maximova, Katerina (School of Public Health Sciences)
Colman, Ian (Epidemiology and Community Medicine)
McGrath, Jennifer (Psychology)
Kozyrskj, Anita (Pediatrics)
School of Public Health Sciences
Date accepted
Graduation date
Master of Science
Degree level
Childhood trauma is a chronic stressor that has been linked to cardiovascular disease (CVD). Evidence also shows that females may have a heightened reactivity to interpersonal and chronic stress than males. The subjects for this study included 6881 members of Statistics Canada's National Population Health Survey. The main objectives were to assess whether women who report childhood trauma are more likely than men who report childhood trauma to have CVD, and possible mediating and moderating factors in the association between childhood trauma and CVD. Our results suggested that the effect of childhood trauma on CVD is heightened among women when compared to men. Stressful life events in adulthood were found to heighten the impact of childhood trauma on CVD, particularly among women. Also, depression, smoking, and poor diet were found to partially mediate the relationship between childhood trauma and CVD. This has important implications for sex differences in CVD risk.
Permission is hereby granted to the University of Alberta Libraries to reproduce single copies of this thesis and to lend or sell such copies for private, scholarly or scientific research purposes only. Where the thesis is converted to, or otherwise made available in digital form, the University of Alberta will advise potential users of the thesis of these terms. The author reserves all other publication and other rights in association with the copyright in the thesis and, except as herein before provided, neither the thesis nor any substantial portion thereof may be printed or otherwise reproduced in any material form whatsoever without the author's prior written permission.
Citation for previous publication

File Details

Date Uploaded
Date Modified
Audit Status
Audits have not yet been run on this file.
File format: pdf (Portable Document Format)
Mime type: application/pdf
File size: 890505
Last modified: 2015:10:12 15:32:19-06:00
Filename: Garad_Hayat_Fall2012.pdf
Original checksum: 741856cd55d2394fa60130e3af612dae
Well formed: false
Valid: false
Status message: Invalid page tree node offset=563674
Status message: Unexpected error in findFonts java.lang.ClassCastException: edu.harvard.hul.ois.jhove.module.pdf.PdfSimpleObject cannot be cast to edu.harvard.hul.ois.jhove.module.pdf.PdfDictionary offset=3025
Status message: Invalid Annotation list offset=795829
Activity of users you follow
User Activity Date