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Permanent link (DOI): https://doi.org/10.7939/R3T93J

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Evaluation of factors associated with resistance to sub-acute ruminal acidosis Open Access

Descriptions

Other title
Subject/Keyword
barley grain
gene expression
precision processing
ruminal acidosis
milk production
volatile fatty acid absorption
dairy cows
volatile fatty acid metabolism
Type of item
Thesis
Degree grantor
University of Alberta
Author or creator
Schlau, Nicole A
Supervisor and department
Oba, Masahito (Agricultural, Food, and Nutritional Science)
Examining committee member and department
Baracos, Vickie (Oncology)
Guan, Leluo (Agricultural, Food, and Nutritional Science)
McFadden, Thomas (Agricultural, Food, and Nutritional Science)
Department
Department of Agricultural, Food, and Nutritional Science
Specialization
Animal Science
Date accepted
2012-09-28T13:55:06Z
Graduation date
2012-09
Degree
Master of Science
Degree level
Master's
Abstract
Sub-acute ruminal acidosis is a digestive disorder experienced by animals fed a high grain diet, and causes substantial economic loss to the dairy industry. The objective of this research was to evaluate novel approaches to manage and prevent sub-acute ruminal acidosis. In Study 1, I found that precision processing barley (processing based on kernel size) does not improve dairy cow productivity. In Study 2, I showed that the extent of ruminal acidosis varies greatly among animals fed a common diet, and that acidosis resistant steers have lower volatile fatty acid (VFA) concentrations compared with susceptible steers, suggesting that resistant steers absorb more VFA, produce less VFA, or both. Further, expression of Na+/H+ exchanger-3, which imports sodium from the cell and exports hydrogen to the ruminal lumen, was higher for resistant steers. These findings suggest that Na+/H+ exchanger-3 is involved in the physiology of VFA absorption, and may play a key role in acidosis resistance.
Language
English
DOI
doi:10.7939/R3T93J
Rights
Permission is hereby granted to the University of Alberta Libraries to reproduce single copies of this thesis and to lend or sell such copies for private, scholarly or scientific research purposes only. Where the thesis is converted to, or otherwise made available in digital form, the University of Alberta will advise potential users of the thesis of these terms. The author reserves all other publication and other rights in association with the copyright in the thesis and, except as herein before provided, neither the thesis nor any substantial portion thereof may be printed or otherwise reproduced in any material form whatsoever without the author's prior written permission.
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